I. Introduction H ETEROGENEITY of polypeptide hormones has been recognized since the
early 1970s. It stems from a variety of sources, including genetic, pretranslational …

Human growth hormone (GH) is a heterogeneous protein hormone consisting of several
isoforms. The sources of this heterogeneity reside at the level of the genome, mRNA …

This work was undertaken to study the heterogeneity of GH in serum and placental and
pituitary extracts and to study GH physiology in pregnant women. Two distinct monoclonal …

Pituitary adenomas, removed surgically from three women with normal or slightly elevated
serum growth hormone levels and no evidence of acromegaly, were studied. The tumor cells …

Lysophosphatidic acid (LPA) is a naturally occurring phospholipid that activates a variety of
biological activities including cell proliferation. Three mammalian LPA receptor (LPAr) …

Purpose: To determine if acute resistance exercise-induced increases in growth hormone
(GH) and insulin-like growth factor-I (IGF-I) were differentially responsive for one or more …

Human growth hormone (GH) is the indispensable hormone for the maintenance of normal
physiological functions of the human body, including the growth, development, metabolism …

GH measurements are complicated by numerous physiologically occurring GH forms, by the
lack of availability of completely specific reagents for the various GH isoforms, and by …

Abstract The 20,000-dalton variant of human GH (20K) is known to circulate in blood, but few
details are known about its plasma transport. A substantial portion of 20K appears to be …

Pituitary growth hormone (GH) is not a single molecular species, but a whole set of similar
molecules, the individual specific characteristics of which constitute the polymorphism of this …