Cancer from the gastrointestinal tract and its associated excretory organs will occur in more
than 300,000 Americans in 2017, with colorectal cancer responsible for> 40% of that …

Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) arise from neuroendocrine
cells found throughout the gastrointestinal tract and islet cells of the pancreas. The incidence …

Pancreatic cancer (PC), particularly its most common form, pancreatic ductal
adenocarcinoma (PDAC), is relatively rare but highly lethal. Knowledge about PC risk …

The widespread use of peptide receptor radionuclide therapy (PRRT) represents a major
therapeutic breakthrough in nuclear medicine, particularly since the introduction of 177Lu …

Purpose Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) form a rare and
remarkably heterogeneous group of tumors. Therefore, establishing personalized therapies …

Background & Aims Small intestinal neuroendocrine tumor (SI-NET) is a rare disease, but its
incidence has increased over the past 4 decades. Understanding the genetic risk factors …

By the strictest of definitions, a genetic driver of tumorigenesis should fulfill two criteria: it
should be altered in a high percentage of patient tumors, and it should also be able to cause …

Pancreatic neuroendocrine neoplasms (PanNENs) contain two primary subtypes with
distinct molecular features and associated clinical outcomes: well-differentiated …

PURPOSE An inherited basis for presumed sporadic neuroendocrine tumor (NET) has been
suggested by evidence of familial clustering of NET and a higher incidence of second …

Small bowel neuroendocrine tumors are rare tumors with an increasing incidence over the
last several decades. Early detection remains challenging because patients commonly …