Rethinking minority stress: A social safety perspective on the health effects of stigma in sexually-diverse and gender-diverse populations

LM Diamond, J Alley - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
For over two decades, the minority stress model has guided research on the health of
sexually-diverse individuals (those who are not exclusively heterosexual) and gender …

Post‐traumatic stress disorder: a state‐of‐the‐art review of evidence and challenges

RA Bryant - World psychiatry, 2019 - Wiley Online Library
Post‐traumatic stress disorder (PTSD) is arguably the most common psychiatric disorder to
arise after exposure to a traumatic event. Since its formal introduction in the DSM‐III in 1980 …

MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study

JM Mitchell, M Bogenschutz, A Lilienstein, C Harrison… - Focus, 2023 - Am Psychiatric Assoc
Post-traumatic stress disorder (PTSD) presents a major public health problem for which
currently available treatments are modestly effective. We report the findings of a randomized …

The generalizability crisis

T Yarkoni - Behavioral and Brain Sciences, 2022 - cambridge.org
Most theories and hypotheses in psychology are verbal in nature, yet their evaluation
overwhelmingly relies on inferential statistical procedures. The validity of the move from …

Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi - Pharmacological Reviews, 2021 - ASPET
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Serotonin and brain function: a tale of two receptors

RL Carhart-Harris, DJ Nutt - Journal of psychopharmacology, 2017 - journals.sagepub.com
Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …

Choosing prediction over explanation in psychology: Lessons from machine learning

T Yarkoni, J Westfall - Perspectives on Psychological …, 2017 - journals.sagepub.com
Psychology has historically been concerned, first and foremost, with explaining the causal
mechanisms that give rise to behavior. Randomized, tightly controlled experiments are …

Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain

D De Gregorio, RJ McLaughlin, L Posa… - Pain, 2019 - journals.lww.com
Clinical studies indicate that cannabidiol (CBD), the primary nonaddictive component of
cannabis that interacts with the serotonin (5-HT) 1A receptor, may possess analgesic and …

The role of 5-HT receptors in depression

CN Yohn, MM Gergues, BA Samuels - Molecular brain, 2017 - Springer
Depression is a polygenic and highly complex psychiatric disorder that remains a major
burden on society. Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) …

Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics

AM Buch, C Liston - Neuropsychopharmacology, 2021 - nature.com
Depression is a heterogeneous and etiologically complex psychiatric syndrome, not a
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …