[HTML][HTML] Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols
Osteoarthritis (OA) is the most prevalent joint degenerative disease leading to irreversible
structural and functional changes in the joint and is a major cause of disability and reduced …
structural and functional changes in the joint and is a major cause of disability and reduced …
Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions
Y Cho, S Jeong, H Kim, D Kang, J Lee… - … & molecular medicine, 2021 - nature.com
Osteoarthritis (OA) is the most common form of arthritis. It is characterized by progressive
destruction of articular cartilage and the development of chronic pain and constitutes a …
destruction of articular cartilage and the development of chronic pain and constitutes a …
NF-κB signaling pathways in osteoarthritic cartilage destruction
MC Choi, J Jo, J Park, HK Kang, Y Park - Cells, 2019 - mdpi.com
Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation,
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …
[HTML][HTML] ROS/oxidative stress signaling in osteoarthritis
P Lepetsos, AG Papavassiliou - … et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
Osteoarthritis is the most common joint disorder with increasing prevalence due to aging of
the population. Its multi-factorial etiology includes oxidative stress and the overproduction of …
the population. Its multi-factorial etiology includes oxidative stress and the overproduction of …
Redox and NF-κB signaling in osteoarthritis
P Lepetsos, KA Papavassiliou… - Free Radical Biology and …, 2019 - Elsevier
Human cells have to deal with the constant production of reactive oxygen species (ROS).
Although ROS overproduction might be harmful to cell biology, there are plenty of data …
Although ROS overproduction might be harmful to cell biology, there are plenty of data …
Role of chondrocytes in cartilage formation, progression of osteoarthritis and cartilage regeneration
H Akkiraju, A Nohe - Journal of developmental biology, 2015 - mdpi.com
Articular cartilage (AC) covers the diarthrodial joints and is responsible for the mechanical
distribution of loads across the joints. The majority of its structure and function is controlled …
distribution of loads across the joints. The majority of its structure and function is controlled …
Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation
Osteoarthritis is one of the leading causes of pain and disability in the aged population due
to articular cartilage damage. This warrants investigation of signaling mechanisms that could …
to articular cartilage damage. This warrants investigation of signaling mechanisms that could …
[HTML][HTML] Microvesicles from human adipose tissue-derived mesenchymal stem cells as a new protective strategy in osteoarthritic chondrocytes
M Tofiño-Vian, MI Guillén, MD Pérez del Caz… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Chronic inflammation contributes to cartilage degeneration during the
progression of osteoarthritis (OA). Adipose tissue-derived mesenchymal stem cells (AD …
progression of osteoarthritis (OA). Adipose tissue-derived mesenchymal stem cells (AD …
[HTML][HTML] Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use
Osteoarthritis (OA) is a heterogeneous disorder. The goals of this review are (1) To stimulate
use of standardized nomenclature for OA that could serve as building blocks for describing …
use of standardized nomenclature for OA that could serve as building blocks for describing …
Curcumin reinforces MSC‐derived exosomes in attenuating osteoarthritis via modulating the miR‐124/NF‐kB and miR‐143/ROCK1/TLR9 signalling pathways
B Qiu, X Xu, P Yi, Y Hao - Journal of Cellular and Molecular …, 2020 - Wiley Online Library
Curcumin treatment was reported to delay the progression of OA, but its underlying
mechanism remains unclear. In this study, we aimed to investigate the molecular …
mechanism remains unclear. In this study, we aimed to investigate the molecular …