One of the factors that increase the effectiveness of the pharmacotherapy used in patients
abusing various types of new psychoactive substances (NPSs) is the proper functioning of …

Non-alcoholic fatty liver disease (NAFLD) is reaching epidemic proportions worldwide.
Moreover, the prevalence of this liver disease is expected to increase rapidly in the near …

Activating autologous stem cells after the implantation of biomaterials is an important
process to initiate bone regeneration. Although several studies have demonstrated the …

Background Osteoporosis, characterized by reduced bone mass and micro-architectural
deterioration, poses a significant public health concern due to increased fracture …

Background and objective With the development of global population aging, comorbidity (≥
2 diseases) is a common health problem among elderly people. Osteoarthritis (OA) and …

Minimally invasive, efficient, and satisfactory treatment for irregular and lacunar bone defects
is still a challenge. Alginate hydrogels serve as promising stem cell (SC) delivery systems for …

Reconstruction of subarticular bone defects is an intractable challenge in orthopedics. The
simultaneous repair of cancellous defects, fractures, and cartilage damage is an ideal …

Alzheimer's disease (AD) is the most common type of cognitive impairment. AD is closely
related to orthopedic diseases, such as osteoporosis and osteoarthritis, in terms of …

Background Lung epithelial cells play important roles in lung inflammation and injury,
although mechanisms remain unclear. Osteopontin (OPN) has essential roles in epithelial …

Osteoporosis is particularly prevalent among postmenopausal women and the elderly. In the
present study, we investigated the effect of the novel small molecule E0924G (N-(4-methoxy …