Here we describe a glycan microarray constructed by using standard robotic microarray
printing technology to couple amine functionalized glycans to an amino-reactive glass slide …

The metal catalyzed azide/alkyne 'click'reaction (a variation of the Huisgen 1, 3‐dipolar
cycloaddition reaction between terminal acetylenes and azides) has vastly increased in …

In the last decade, glycan microarrays have revolutionized the analysis of the specificity of
glycan-binding proteins (GBPs), providing information that simultaneously illuminates the …

Our understanding of the different glycoconjugates present on cells, proteins and entire
organisms is lagging far behind advances in genomics and proteomics. Carbohydrate …

Carbohydrate-specific antibodies are widespread among all classes of immunoglobulins.
Despite their broad occurrence, little is known about their formation and biological …

The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is one of the most broadly
applicable and easy-to-handle reactions in the arsenal of organic chemistry. However, the …

The increasing need for materials with tightly controlled structures will continue to fuel the
induction of synthetic organic concepts into materials science. One powerful example is the …

Although the reaction between an azide and a phosphane to form an aza‐ylide was
discovered by Hermann Staudinger more than 80 years ago and has found widespread …

Living/controlled polymerization techniques have enabled the synthesis of a large variety of
different well-defined (co) polymer structures. In addition, the use of click chemistry in …

The interaction of small molecules with DNA plays an essential role in many biological
processes. As DNA is often the target for majority of anticancer and antibiotic drugs, study …