When CuAAC'click chemistry'goes heterogeneous

S Chassaing, V Bénéteau, P Pale - Catalysis Science & Technology, 2016 - pubs.rsc.org
Within the green chemistry context, heterogeneous catalysis applied to organic synthesis is
becoming an increasingly important field, bringing its own innovation and specific properties …

Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12

DA Calarese, HK Lee, CY Huang… - Proceedings of the …, 2005 - National Acad Sciences
Human antibody 2G12 neutralizes a broad range of HIV-1 isolates. Hence, molecular
characterization of its epitope, which corresponds to a conserved cluster of oligomannoses …

Azide/alkyne-“click” reactions: applications in material science and organic synthesis

WH Binder, C Kluger - Current Organic Chemistry, 2006 - ingentaconnect.com
The fixation of ligands onto molecules, surfaces and materials by use of reactions using a
simple and unified chemistry is among the everlasting desires of chemists. Besides the …

Designing polymers with sugar-based advantages for bioactive delivery applications

Y Zhang, JW Chan, A Moretti, KE Uhrich - Journal of Controlled Release, 2015 - Elsevier
Sugar-based polymers have been extensively explored as a means to increase drug
delivery systems' biocompatibility and biodegradation. Here, we review the use of sugar …

[HTML][HTML] The use of carbohydrate microarrays to study carbohydrate-cell interactions and to detect pathogens

MD Disney, PH Seeberger - Chemistry & biology, 2004 - cell.com
The use of carbohydrate microarrays to investigate the carbohydrate binding specificities of
bacteria, to detect pathogens, and to screen antiadhesion therapeutics is reported. This …

Chemical approaches to glycobiology

LL Kiessling, RA Splain - Annual review of biochemistry, 2010 - annualreviews.org
Glycans are ubiquitous components of all organisms. Efforts to elucidate glycan function and
to understand how they are assembled and disassembled can reap benefits in fields …

Carbohydrate microarrays—a new set of technologies at the frontiers of glycomics

T Feizi, F Fazio, W Chai, CH Wong - Current opinion in structural biology, 2003 - Elsevier
Carbohydrate microarray technologies are new developments at the frontiers of glycomics.
Results of 'proof of concept'experiments with carbohydrate-binding proteins of the immune …

Multivalent ligand presentation as a central concept to study intricate carbohydrate–protein interactions

N Jayaraman - Chemical society reviews, 2009 - pubs.rsc.org
Studying the weak binding affinities between carbohydrates and proteins has been a central
theme in sustained efforts to uncover intricate details of this class of biomolecular interaction …

Glycomics: a pathway to a class of new and improved therapeutics

Z Shriver, S Raguram, R Sasisekharan - Nature Reviews Drug …, 2004 - nature.com
Complex glycans that are located at the surface of cells, deposited in the extracellular matrix
and attached to soluble signalling molecules have a crucial role in the phenotypic …

[HTML][HTML] Highly Efficient Chemoenzymatic Synthesis of Naturally Occurring and Unnatural α2, 6-Linked Sialosides: A P. damsela α2, 6-Sialyltransferase with Extremely …

H Yu, S Huang, H Chokhawala, M Sun… - … (International ed. in …, 2006 - ncbi.nlm.nih.gov
Sialic acids are a family of α-keto acids with a 9-carbon backbone. They have been
predominantly found as terminal carbohydrate units on glycoproteins and glycolipids of …