Click chemistry is a powerful chemical reaction with excellent bioorthogonality features:
biocompatible, rapid and highly specific in biological environments. For glycobiology …

Chemoenzymatic synthesis, which combines the flexibility of chemical synthesis and the
high selectivity of enzymatic synthesis, is a powerful approach to obtain complex …

Many biologically active natural products are constrained by macrocyclization and modified
with carbohydrates. These two types of modifications are essential for their biological …

Carbohydrate chains of glycoproteins, glycolipids, proteoglycans, and polysaccharides
mediate processes of biological and medical importance through their interactions with …

Glycan arrays are increasingly popular tools for probing the ligand specificities of glycan-
binding receptors,[1] antibodies,[2] and enzymes.[1c, d, f, 3] In a typical architecture, the …

Glycobiology is the comprehensive biological investigation of carbohydrates. The study of
the role and function of complex carbohydrates often requires the attachment of …

Many different reagents and methodologies have been utilised for the modification of
synthetic and biological macromolecular systems. In addition, an area of intense research at …

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A covalent array for the display of complex oligosaccharides in microtiter plates has been
developed. This strategy is conducive to the display of carbohydrates to proteins of interest …

The biological significance of glycans in the post‐genomic era requires the development of
new technologies to enable functional studies of carbohydrates in a high‐throughput …