The potential therapeutic use of some Cannabis sativa plant compounds has been attracting
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …

Background: Among the many cannabinoids in the cannabis plant, cannabidiol (CBD) is a
compound that does not produce the typical subjective effects of marijuana. Objectives: The …

Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum
drug that in recent years has drawn increasing interest as a treatment for a range of …

Learning to associate cues or contexts with potential threats or rewards is adaptive and
enhances survival. Both aversive and appetitive memories are therefore powerful drivers of …

Cannabis sativa (cannabis) is one of the oldest plants cultivated by men. Cannabidiol (CBD)
is the major non-psychomimetic compound derived from cannabis. It has been proposed to …

Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric
disorders, including anxiety, psychosis, and depression. The mechanisms responsible for …

The prelimbic division (PrL) of the medial prefrontal cortex (mPFC) is a cerebral division that
is putatively implicated in the chronic pain and depression. We investigated the activity of …

Background: Preclinical research suggests that cannabidiol (CBD) may have therapeutic
potential in pathological anxiety. Dosing guidelines to inform future human studies are …

Background: Cannabis sativa-derived substances such as cannabidiol (CBD) have attracted
increasing clinical interest and consist in a new perspective for treating some neurological …

Long-term single housing increases aggressive behavior in mice, a condition named
isolation-induced aggression or territorial aggression, which can be attenuated by anxiolytic …