New atypical antipsychotics in the treatment of schizophrenia and depression

J Orzelska-Górka, J Mikulska, A Wiszniewska… - International journal of …, 2022 - mdpi.com
Schizophrenia and depression are heterogeneous disorders. The complex
pathomechanism of the diseases imply that medication responses vary across patients …

Pharmacological activities and pharmacokinetics of liquiritin: a review

J Qin, J Chen, F Peng, C Sun, Y Lei, G Chen… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Liquiritin is a flavonoid derived from Radix et Rhizoma
Glycyrrhizae, which is a widely used traditional Chinese medicine with the effects of …

Microbiota–gut–brain axis and epilepsy: a review on mechanisms and potential therapeutics

M Ding, Y Lang, H Shu, J Shao, L Cui - Frontiers in Immunology, 2021 - frontiersin.org
The gut–brain axis refers to the bidirectional communication between the gut and brain, and
regulates intestinal homeostasis and the central nervous system via neural networks and …

Antidepressant-like effects of psychedelics in a chronic despair mouse model: is the 5-HT2A receptor the unique player?

M Sekssaoui, J Bockaert, P Marin… - …, 2024 - nature.com
Major depressive disorder (MDD) is one of the most disabling psychiatric disorders in the
world. First-line treatments such as selective serotonin reuptake inhibitors (SSRIs) still have …

Functional dimerization of serotonin receptors: role in health and depressive disorders

EV Mitroshina, EA Marasanova… - International journal of …, 2023 - mdpi.com
Understanding the neurobiological underpinnings of depressive disorder constitutes a
pressing challenge in the fields of psychiatry and neurobiology. Depression represents one …

Global warming and glyphosate toxicity (I): Adult zebrafish modelling with behavioural, immunohistochemical and metabolomic approaches

E Sulukan, A Baran, O Şenol, M Kankaynar… - Science of The Total …, 2023 - Elsevier
Global warming further increases the toxic threat of environmental pollutants on organisms.
In order to reveal the dimensions of this threat more clearly, it is of great importance that the …

Molecular pathways of the therapeutic effects of ayahuasca, a botanical psychedelic and potential rapid-acting antidepressant

GN Rossi, LTL Guerra, GB Baker, SM Dursun… - Biomolecules, 2022 - mdpi.com
Ayahuasca is a psychoactive brew traditionally used in indigenous and religious rituals and
ceremonies in South America for its therapeutic, psychedelic, and entheogenic effects. It is …

[HTML][HTML] A Bibliometric and Visual Analysis of Single Nucleotide Polymorphism Studies in Depression

Z Zhang, Y Yang, W Kong, S Huang, Y Tan… - Current …, 2023 - ncbi.nlm.nih.gov
Background Genetic polymorphism has been proven to have an important association with
depression, which can influence the risk of developing depression, the efficacy of …

Discovery and In Vitro Characterization of SPL028: Deuterated N,N-Dimethyltryptamine

M Layzell, P Rands, M Good, Z Joel… - ACS Medicinal …, 2023 - ACS Publications
The psychedelic N, N-dimethyltryptamine (DMT) is in clinical development for the treatment
of major depressive disorder. However, when administered via intravenous infusion, its …

The gut odorant receptor and taste receptor make sense of dietary components: A focus on gut hormone secretion

Y Wang, R Geng, Y Zhao, J Fang, M Li… - Critical Reviews in …, 2023 - Taylor & Francis
Odorant receptors (ORs) and taste receptors (TRs) are expressed primarily in the nose and
tongue in which they transduce electrical signals to the brain. Advances in deciphering the …