Patients with Parkinson's disease have a number of specific visual disturbances. These
include changes in colour vision and contrast sensitivity and difficulties with complex visual …

In addition, we introduce two other recent methods as future directions for estimating cortical
morphological changes: a multi-modal parcellation method using structural and functional …

Magnetic resonance imaging (MRI) is a non-invasive technique which can provide
comprehensive, multi-parametric information on brain anatomy, function and metabolism …

The purpose of this work was to evaluate changes in the connectivity patterns of a set of
cognitively relevant, dynamically interrelated brain networks in association with cognitive …

Mild cognitive impairment in Parkinson's disease is associated with progression to dementia
(Parkinson's disease dementia) in a majority of patients. Determining structural imaging …

Here we test the hypothesis that the neurodegenerative process in Parkinson's disease (PD)
moves stereotypically along neural networks, possibly reflecting the spread of toxic alpha …

The folding of the human cerebral cortex is a highly genetically regulated process that
allows for a much larger surface area to fit into the cranial vault and optimizes functional …

Parkinson's disease varies in severity and age of onset. One source of this variability is sex.
Males are twice as likely as females to develop Parkinson's disease, and tend to have more …

Cognitive impairment is common in PD, even in early stages. The construct of mild cognitive
impairment has been used to identify clinically evident cognitive impairment without …

Objective To investigate the pattern of cortical thinning in Parkinson's disease (PD) across
different disease stages and to elucidate to what extent cortical thinning is related to …