Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Can muscle typology explain the inter‐individual variability in resistance training adaptations?

K Van Vossel, J Hardeel… - The Journal of …, 2023 - Wiley Online Library
Considerable inter‐individual heterogeneity exists in the muscular adaptations to resistance
training. It has been proposed that fast‐twitch fibres are more sensitive to hypertrophic …

Myofiber hypertrophy adaptations following 6 weeks of low-load resistance training with blood flow restriction in untrained males and females

TM Reece, JS Godwin, MJ Strube… - Journal of Applied …, 2023 - journals.physiology.org
The effects of low-load resistance training with blood flow restriction (BFR) on hypertrophy of
type I/II myofibers remains unclear, especially in females. The purpose of the present study …

Proteolytic markers associated with a gain and loss of leg muscle mass with resistance training followed by high‐intensity interval training

JM Michel, JS Godwin, DL Plotkin… - Experimental …, 2023 - Wiley Online Library
We recently reported that vastus lateralis (VL) cross‐sectional area (CSA) increases after 7
weeks of resistance training (RT, 2 days/week), with declines occurring following 7 weeks of …

Resistance training diminishes mitochondrial adaptations to subsequent endurance training in healthy untrained men

PHC Mesquita, JS Godwin, BA Ruple… - The Journal of …, 2023 - Wiley Online Library
We investigated the effects of performing a period of resistance training (RT) on the
performance and molecular adaptations to a subsequent period of endurance training (ET) …

The relationship between muscle thickness and pennation angle is mediated by fascicle length in the muscles of the lower extremities

S Martin-Rodriguez, JJ Gonzalez-Henriquez… - Scientific Reports, 2024 - nature.com
Muscle morphological architecture, a crucial determinant of muscle function, has fascinated
researchers since the Renaissance. Imaging techniques enable the assessment of …

Ultrasound assessment of rectus femoris pennation angle and echogenicity. Their association with muscle functional measures and fat infiltration measured by CT …

D Bunout, S Gonzalez, M Canales, G Barrera… - Clinical Nutrition …, 2023 - Elsevier
Background & aims Ultrasound can be used to measure the pennation angle between
muscle fiver and the presumed axis of force generation and muscle echogenicity as an …

Comparison of Traditional and Advanced Resistance Training Paradigms on Muscle Hypertrophy in Trained Individuals: A Systematic Review and Meta‐Analysis

PAB Fonseca, BN Ide, DJ Oranchuk… - Translational Sports …, 2023 - Wiley Online Library
Trained individuals may require variations in training stimuli and advanced resistance
training paradigms (ADV) to increase skeletal muscle hypertrophy. However, no meta …

Influence of intramuscular steroid receptor content and fiber capillarization on skeletal muscle hypertrophy

K Van Vossel, J Hardeel… - … Journal of Medicine …, 2024 - Wiley Online Library
Multiple intramuscular variables have been proposed to explain the high variability in
resistance training induced muscle hypertrophy across humans. This study investigated if …

An optimized approach to study nanoscale sarcomere structure utilizing super-resolution microscopy with nanobodies

CM Douglas, JE Bird, D Kopinke, KA Esser - Plos one, 2024 - journals.plos.org
The sarcomere is the fundamental contractile unit in skeletal muscle, and the regularity of its
structure is critical for function. Emerging data demonstrates that nanoscale changes to the …