[HTML][HTML] The crosstalk between glucose metabolism and telomerase regulation in cancer

M Huang, M Liu, R Wang, Y Man, H Zhou, ZX Xu… - Biomedicine & …, 2024 - Elsevier
Accumulated alterations in metabolic control provide energy and anabolic demands for
enhanced cancer cell proliferation. Exemplified by the Warburg effect, changes in glucose …

[HTML][HTML] Unlocking longevity: the role of telomeres and its targeting interventions

M Schellnegger, E Hofmann, M Carnieletto… - Frontiers in …, 2024 - frontiersin.org
Average life expectancy has been steadily increasing in developed countries worldwide.
These demographic changes are associated with an ever-growing social and economic …

[HTML][HTML] LILRB2 inhibition enhances radiation sensitivity in non-small cell lung cancer by attenuating radiation-induced senescence

X Chen, M Yuan, T Zhong, M Wang, F Wu, J Lu, D Sun… - Cancer Letters, 2024 - Elsevier
Radiotherapy (RT) in non-small cell lung cancer (NSCLC) triggers cellular senescence,
complicating tumor microenvironments and affecting treatment outcomes. This study …

[HTML][HTML] In silico approach for predicting the bioactive compound of Cyperus rotundus to inhibit NF-kB and iNOS signaling pathways

M Setiawan, SM Agustini, Patmawati… - Brazilian Journal of …, 2024 - SciELO Brasil
This study aims to evaluate the anti-cancer-related inflammation activity of Cyperus rotundus
bioactive compounds. The component of C. rotundus was analyzed using LC-HRMS. The …

Aplicaciones de la multiómica de célula única en la investigación del cáncer

O Arrieta, R Rosell, AF Cardona - Medicina, 2023 - revistamedicina.net
Precision oncology, defined as molecular profiling of tumors to identify targetable alterations,
is rapidly developing, and has entered the mainstream clinical practice. Genomic testing …

مطالعه اثر پاتوژنسیتی تغییرات نوکلئوتیدی جدید در ناحیه پروموتری ژن TERT در بیماران مبتلا به تومور مغزی از نوع گلیوبلاستوما

اولیا, فرزانه, حیدری, خاتمی, مهری, ضیایی… - ماهنامه علمی پ‍ژوهشی دانشگاه …, 2024‎ - jssu.ssu.ac.ir
مقدمه: علی‌رغم دهه‌ها تلاش در تشخیص و درمان تومورهای مغزی، همچنان این نوع تومورها، در بین
کشنده‌ترین انواع سرطان‌ها دسته‌بندی می‌شوند. فعال‌شدن آنزیم تلومراز، به‌عنوان یک عامل اساسی در …