Trehalose: a key organic osmolyte effectively involved in plant abiotic stress tolerance
F Kosar, NA Akram, M Sadiq, F Al-Qurainy… - Journal of Plant Growth …, 2019 - Springer
Trehalose is a natural non-reducing sugar that is found in the vast majority of organisms
such as bacteria, yeasts, invertebrates and even in plants. Regarding its features, it is …
such as bacteria, yeasts, invertebrates and even in plants. Regarding its features, it is …
Are aberrant phase transitions a driver of cellular aging?
Why do cells age? Recent advances show that the cytoplasm is organized into many
membrane‐less compartments via a process known as phase separation, which ensures …
membrane‐less compartments via a process known as phase separation, which ensures …
[HTML][HTML] Tardigrades use intrinsically disordered proteins to survive desiccation
Tardigrades are microscopic animals that survive a remarkable array of stresses, including
desiccation. How tardigrades survive desiccation has remained a mystery for more than 250 …
desiccation. How tardigrades survive desiccation has remained a mystery for more than 250 …
Trehalose-induced activation of autophagy improves cardiac remodeling after myocardial infarction
S Sciarretta, D Yee, N Nagarajan, F Bianchi… - Journal of the American …, 2018 - jacc.org
Background: Trehalose (TRE) is a natural, nonreducing disaccharide synthesized by lower
organisms. TRE exhibits an extraordinary ability to protect cells against different kinds of …
organisms. TRE exhibits an extraordinary ability to protect cells against different kinds of …
Intrinsically disordered proteins drive emergence and inheritance of biological traits
S Chakrabortee, JS Byers, S Jones, DM Garcia… - Cell, 2016 - cell.com
Prions are a paradigm-shifting mechanism of inheritance in which phenotypes are encoded
by self-templating protein conformations rather than nucleic acids. Here, we examine the …
by self-templating protein conformations rather than nucleic acids. Here, we examine the …
Protein-based inheritance: epigenetics beyond the chromosome
Epigenetics refers to changes in phenotype that are not rooted in DNA sequence. This
phenomenon has largely been studied in the context of chromatin modification. Yet many …
phenomenon has largely been studied in the context of chromatin modification. Yet many …
Relevance and regulation of cell density
GE Neurohr, A Amon - Trends in cell biology, 2020 - cell.com
Cell density shows very little variation within a given cell type. For example, in humans
variability in cell density among cells of a given cell type is 100 times smaller than variation …
variability in cell density among cells of a given cell type is 100 times smaller than variation …
Trehalose and tardigrade CAHS proteins work synergistically to promote desiccation tolerance
Tardigrades are microscopic animals renowned for their ability to survive extreme
desiccation. Unlike many desiccation-tolerant organisms that accumulate high levels of the …
desiccation. Unlike many desiccation-tolerant organisms that accumulate high levels of the …
Transcriptional response provides insights into the effect of chronic polystyrene nanoplastic exposure on Daphnia pulex
Nanoplastic pollution is widespread and persistent across global water systems and can
cause a negative effect on aquatic organisms, especially the zooplankter which is the …
cause a negative effect on aquatic organisms, especially the zooplankter which is the …
Protein phase separation as a stress survival strategy
TM Franzmann, S Alberti - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
Cells under stress must adjust their physiology, metabolism, and architecture to adapt to the
new conditions. Most importantly, they must down-regulate general gene expression, but at …
new conditions. Most importantly, they must down-regulate general gene expression, but at …