Long-term preservation of bacteriophage antimicrobials using sugar glasses

V Leung, A Szewczyk, J Chau… - ACS Biomaterials …, 2017 - ACS Publications
The antimicrobial activity of LISTEX P100, Salmonella CG4, and E. coli AG10
bacteriophages were preserved in pullulan-trehalose mixture as dried films and as coatings …

[HTML][HTML] Mechanisms and evolution of resistance to environmental extremes in animals

TC Boothby - EvoDevo, 2019 - Springer
When animals are exposed to an extreme environmental stress, one of three possible
outcomes takes place: the animal dies, the animal avoids the environmental stress and …

Light modulates important pathogenic determinants and virulence in ESKAPE pathogens Acinetobacter baumannii, Pseudomonas aeruginosa, and Staphylococcus …

MR Tuttobene, JF Pérez, ES Pavesi… - Journal of …, 2021 - Am Soc Microbiol
Light sensing has been extensively characterized in the human pathogen Acinetobacter
baumannii at environmental temperatures. However, the influence of light on the physiology …

BioSentinel: Long-Term Saccharomyces cerevisiae Preservation for a Deep Space Biosensor Mission

SR Santa Maria, DB Marina, S Massaro Tieze… - Astrobiology, 2023 - liebertpub.com
The biological risks of the deep space environment must be elucidated to enable a new era
of human exploration and scientific discovery beyond low earth orbit (LEO). There is a …

[HTML][HTML] Molecular characterization of Tps1 and Treh genes in Drosophila and their role in body water homeostasis

M Yoshida, H Matsuda, H Kubo, T Nishimura - Scientific Reports, 2016 - nature.com
In insects, trehalose serves as the main sugar component of haemolymph. Trehalose is also
recognized as a mediator of desiccation survival due to its proposed ability to stabilize …

[HTML][HTML] Adaptation to dietary conditions by trehalose metabolism in Drosophila

T Yasugi, T Yamada, T Nishimura - Scientific Reports, 2017 - nature.com
Trehalose is a non-reducing disaccharide that serves as the main sugar component of
haemolymph in insects. Trehalose hydrolysis enzyme, called trehalase, is highly conserved …

[HTML][HTML] Liposomes with diverse compositions are protected during desiccation by LEA proteins from Artemia franciscana and trehalose

DS Moore, R Hansen, SC Hand - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
Abstract Intracellular accumulation of Late Embryogenesis Abundant (LEA) proteins and the
disaccharide trehalose is associated with cellular desiccation tolerance in a number of …

[HTML][HTML] Eggs of the mosquito Aedes aegypti survive desiccation by rewiring their polyamine and lipid metabolism

A Prasad, S Sreedharan, B Bakthavachalu… - PLoS Biology, 2023 - journals.plos.org
Upon water loss, some organisms pause their life cycles and escape death. While
widespread in microbes, this is less common in animals. Aedes mosquitoes are vectors for …

BioSentinel: a biofluidic nanosatellite monitoring microbial growth and activity in deep space

MR Padgen, LC Liddell, SR Bhardwaj, D Gentry… - Astrobiology, 2023 - liebertpub.com
Small satellite technologies, particularly CubeSats, are enabling breakthrough research in
space. Over the past 15 years, NASA Ames Research Center has developed and flown half …

[HTML][HTML] Synergy between the small intrinsically disordered protein Hsp12 and trehalose sustain viability after severe desiccation

SX Kim, G Camdere, X Hu, D Koshland, H Tapia - Elife, 2018 - elifesciences.org
Anhydrobiotes are rare microbes, plants and animals that tolerate severe water loss.
Understanding the molecular basis for their desiccation tolerance may provide novel …