An update on antifungal targets and mechanisms of resistance in Candida albicans

RA Akins - Medical mycology, 2005 - academic.oup.com
Much progress has been made in the last decade in identifying genes responsible for
antifungal resistance in Candida albicans. Attention has focused on five major C. albicans …

Combination and sequential antifungal therapy for invasive aspergillosis: review of published in vitro and in vivo interactions and 6281 clinical cases from 1966 to …

WJ Steinbach, DA Stevens… - Clinical Infectious …, 2003 - academic.oup.com
The development of newer antifungal drugs is creating new potential combination therapies
to combat the dismal mortality rate associated with invasive aspergillosis (IA). The efficacy of …

Recent advancements in anti-leishmanial research: Synthetic strategies and structural activity relationships

O Gupta, T Pradhan, R Bhatia, V Monga - European Journal of Medicinal …, 2021 - Elsevier
Leishmaniasis is a parasitic neglected tropical disease caused by various species of
Leishmania parasite. Despite tremendous advancements in the therapeutic sector and drug …

Antimicrobial activity and spectrum of rifaximin, a new topical rifamycin derivative

WW Hoover, EH Gerlach, DJ Hoban… - … and infectious disease, 1993 - Elsevier
Rifaximin, a rifamycin derivative, was evaluated in vitro to assess its spectrum and potency
against a wide variety of bacteria, yeasts, viruses, and parasites. High concentrations of …

Fungal infections in solid organ transplant recipients

S Hadley, AW Karchmer - Infectious disease clinics of North America, 1995 - Elsevier
Despite advances in surgical technique and immunosuppressive regimens, infections
remain major causes of morbidity and mortality in patients undergoing solid-organ …

In vitro activity of fluvastatin, a cholesterol-lowering agent, and synergy with flucanazole and itraconazole against Candida species and Cryptococcus neoformans

NX Chin, I Weitzman, P Della-Latta - Antimicrobial agents and …, 1997 - Am Soc Microbiol
Fluvastatin, a cholesterol-lowering drug, exhibited minimal activity (MICs of 64 to> 128
microg/ml) against Candida species and Cryptococcus neoformans. When fluvastatin was …

In vitro antifungal activity of the berberine and its synergism with fluconazole

RS Iwazaki, EH Endo, T Ueda-Nakamura… - Antonie Van …, 2010 - Springer
Berberine with and without fluconazole was tested by an agar disk diffusion assay in which
clinical isolates of Candida albicans were applied onto yeast extract-peptone-dextrose agar …

Demonstration of synergy with fluconazole and either ibuprofen, sodium salicylate, or propylparaben against Candida albicans in vitro

EM Scott, VN Tariq, RM McCrory - Antimicrobial agents and …, 1995 - Am Soc Microbiol
The combination of fluconazole with either ibuprofen, sodium salicylate, or propylparaben
resulted in synergistic activity (fractional inhibitory index,< 0.5) against Candida albicans …

Synergistic antifungal activity of statin–azole associations as witnessed by Saccharomyces cerevisiae-and Candida utilis-bioassays and ergosterol quantification

ME Cabral, LIC Figueroa, JI Fariña - Revista Iberoamericana de Micología, 2013 - Elsevier
BACKGROUND: Frequent opportunist fungal infections and the resistance to available
antifungal drugs promoted the development of new alternatives for treatment, like antifungal …

[PDF][PDF] Amphotericin B versus amphotericin B plus 5-flucytosine: poor results in the treatment of proven systemic mycoses in neutropenic patients

PE Verweij, J Meis, JP Donnelly, BE De Pauw… - Infection, 1994 - researchgate.net
Twenty-eight neutropenic (< 500 granulocytes/gl) adults with microbiologically or
histologically proven systemic mycosis were randomly assigned to receive either …