Delivering drugs to tubular cells and organelles: the application of nanodrugs in acute kidney injury
Z Li, X Fan, J Fan, W Zhang, J Liu, B Liu, H Zhang - Nanomedicine, 2023 - Taylor & Francis
Acute kidney injury (AKI) is a common clinical syndrome with limited treatment options and
high mortality rates. Proximal tubular epithelial cells (PTECs) play a key role in AKI …
high mortality rates. Proximal tubular epithelial cells (PTECs) play a key role in AKI …
Physiological principles underlying the kidney targeting of renal nanomedicines
Kidney disease affects more than 10% of the global population and is associated with
considerable morbidity and mortality, highlighting a need for new therapeutic options …
considerable morbidity and mortality, highlighting a need for new therapeutic options …
Clustered cobalt nanodots initiate ferroptosis by upregulating heme oxygenase 1 for radiotherapy sensitization
J Zhao, Y Chen, T Xiong, S Han, C Li, Y He, Y He… - Small, 2023 - Wiley Online Library
High cobalt (Co) levels in tumors are associated with good clinical prognosis. An anticancer
regimen that increases intratumoral Co through targeted nanomaterial delivery is proposed …
regimen that increases intratumoral Co through targeted nanomaterial delivery is proposed …
Autophagy of OTUD5 destabilizes GPX4 to confer ferroptosis-dependent kidney injury
LK Chu, X Cao, L Wan, Q Diao, Y Zhu, Y Kan… - Nature …, 2023 - nature.com
Ferroptosis is an iron-dependent programmed cell death associated with severe kidney
diseases, linked to decreased glutathione peroxidase 4 (GPX4). However, the spatial …
diseases, linked to decreased glutathione peroxidase 4 (GPX4). However, the spatial …
[HTML][HTML] Injectable hydrogel with selenium nanoparticles delivery for sustained glutathione peroxidase activation and enhanced osteoarthritis therapeutics
W Hu, X Yao, Y Li, J Li, J Zhang, Z Zou, F Kang… - Materials Today Bio, 2023 - Elsevier
Reactive oxygen burst in articular chondrocytes is a major contributor to osteoarthritis
progression. Although selenium is indispensable role in the antioxidant process, the narrow …
progression. Although selenium is indispensable role in the antioxidant process, the narrow …
Nano‑selenium alleviates the pyroptosis of cardiovascular endothelial cells in chicken induced by decabromodiphenyl ether through ERS-TXNIP-NLRP3 pathway
Y Jiang, B Dong, X Jiao, J Shan, C Fang… - Science of The Total …, 2024 - Elsevier
Abstract Decabromodiphenyl ether (BDE-209) is one of the most widely used flame
retardants that can infect domestic and wildlife through contaminated feed. Nano‑selenium …
retardants that can infect domestic and wildlife through contaminated feed. Nano‑selenium …
Self‐Assembly of Selenium‐Doped Carbon Quantum Dots as Antioxidants for Hepatic Ischemia‐Reperfusion Injury Management
B Bai, S Qi, K Yang, X Yu, R Jian, T Zhang, D Wang… - Small, 2023 - Wiley Online Library
Hepatic ischemia‐reperfusion injury (HIRI) is a critical complication after liver surgery that
negatively affects surgical outcomes of patients with the end‐stage liver‐related disease …
negatively affects surgical outcomes of patients with the end‐stage liver‐related disease …
Black phosphorus nanosheets suppress oxidative damage of stem cells for improved neurological recovery
Stem cell transplantation has wide application prospects in tissue injury recovery, especially
in neurological recovery. However, the low survival rate of stem cells after transplanted to …
in neurological recovery. However, the low survival rate of stem cells after transplanted to …
Nanosystems for oxidative stress regulation in the anti-inflammatory therapy of acute kidney injury
Y Wang, H Jiang, L Zhang, P Yao, S Wang… - … in Bioengineering and …, 2023 - frontiersin.org
Acute kidney injury (AKI) is a clinical syndrome that results from a rapid decline in renal
structure or renal functional impairment with the main pathological feature of sublethal and …
structure or renal functional impairment with the main pathological feature of sublethal and …
Nephroprotective effects of selenium nanoparticles against sodium arsenite-induced damages
S Li, X Dong, L Xu, Z Wu - International Journal of Nanomedicine, 2023 - Taylor & Francis
Introduction The potential effects of selenium nanoparticles (SeNPs) administration on
arsenic exposure-mediated nephrotoxicity by alleviating fibrosis, inflammation, oxidative …
arsenic exposure-mediated nephrotoxicity by alleviating fibrosis, inflammation, oxidative …