Prevention and management of radiation-induced dermatitis, mucositis, and xerostomia

LJ Radvansky, MB Pace… - American journal of health …, 2013 - academic.oup.com
Purpose Current strategies for preventing and managing radiation-induced dermatitis,
mucositis, and xerostomia are reviewed, with an emphasis on pharmacologic interventions …

Diagnosis, Prevention, and Treatment of Radiotherapy‐Induced Xerostomia: A Review

Y Li, X Li, R Pang, G Yang, M Tian, T Zhao… - Journal of …, 2022 - Wiley Online Library
In patients with head and neck cancer, irradiation (IR)‐sensitive salivary gland (SG) tissue is
highly prone to damage during radiotherapy (RT). This leads to SG hypofunction and …

[HTML][HTML] Dietary nitrate supplementation prevents radiotherapy-induced xerostomia

X Feng, Z Wu, J Xu, Y Xu, B Zhao, B Pang, X Qu, L Hu… - Elife, 2021 - elifesciences.org
Management of salivary gland hypofunction caused by irradiation (IR) therapy for head and
neck cancer remains lack of effective treatments. Salivary glands, especially the parotid …

Oral microbiome and onset of oral mucositis in patients with squamous cell carcinoma of the head and neck

CC Reyes‐Gibby, J Wang, L Zhang, CB Peterson… - Cancer, 2020 - Wiley Online Library
Background Oral mucositis (OM) is a debilitating sequela for patients treated for squamous
cell carcinoma of the head and neck (HNSCC). This study investigated whether oral …

Patient-reported outcomes following parotid-sparing intensity-modulated radiotherapy for head and neck cancer. How important is dysphagia?

JWG Roe, MJ Drinnan, PN Carding, KJ Harrington… - Oral oncology, 2014 - Elsevier
Objectives: Swallowing can be significantly affected during and following radiotherapy for
head and neck cancer (HNC). The purpose of this study was to understand:(1) the trajectory …

Implantable three-dimensional salivary spheroid assemblies demonstrate fluid and protein secretory responses to neurotransmitters

S Pradhan-Bhatt, DA Harrington, RL Duncan… - … engineering Part A, 2013 - liebertpub.com
Radiation treatment in patients with head and neck tumors commonly results in
hyposalivation and xerostomia due to the loss of fluid-secreting salivary acinar cells …

[HTML][HTML] Paracrine effects of bone marrow soup restore organ function, regeneration, and repair in salivary glands damaged by irradiation

SD Tran, Y Liu, D Xia, OM Maria, S Khalili, RWJ Wang… - PLoS …, 2013 - journals.plos.org
Background There are reports that bone marrow cell (BM) transplants repaired irradiated
salivary glands (SGs) and re-established saliva secretion. However, the mechanisms of …

Malnutrition and quality of life in patients treated for oral or oropharyngeal cancer

H Jager‐Wittenaar, PU Dijkstra, A Vissink… - Head & …, 2011 - Wiley Online Library
Background. This study assessed whether malnourished patients score lower on quality of
life after treatment for oral/oropharyngeal cancer. Methods. Malnutrition (weight loss≥ 10 …

Salivary gland cell differentiation and organization on micropatterned PLGA nanofiber craters

DA Soscia, SJ Sequeira, RA Schramm… - Biomaterials, 2013 - Elsevier
There is a need for an artificial salivary gland as a long-term remedy for patients suffering
from salivary hypofunction, a leading cause of chronic xerostomia (dry mouth). Current …

Effect of low-level laser therapy on radiotherapy-induced hyposalivation and xerostomia: a pilot study

J Saleh, MAZ Figueiredo, K Cherubini… - … and laser surgery, 2014 - liebertpub.com
Objective: The present pilot study aimed to assess the effect of low-level laser therapy
(LLLT) on hyposalivation and xerostomia as a consequence of head and neck radiotherapy …