Apparent changes in the epidemiology and severity of multiple sclerosis

N Koch-Henriksen, M Magyari - Nature Reviews Neurology, 2021 - nature.com
Multiple sclerosis (MS) is an immunological disease that causes acute inflammatory lesions
and chronic inflammation in the CNS, leading to tissue damage and disability. As awareness …

[HTML][HTML] Multiple sclerosis incidence: a systematic review of change over time by geographical region

J Lane, HS Ng, C Poyser, RM Lucas… - Multiple Sclerosis and …, 2022 - Elsevier
Background The incidence of multiple sclerosis (MS) has reportedly increased over time;
however, change in MS incidence has not been rigorously assessed globally. Methods We …

ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis

X Montalban, R Gold, AJ Thompson… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: Multiple sclerosis (MS) is a complex disease with new drugs becoming
available in the past years. There is a need for a reference tool compiling current data to aid …

Incidence of MS has increased markedly over six decades in Denmark particularly with late onset and in women

N Koch-Henriksen, LC Thygesen, E Stenager… - Neurology, 2018 - AAN Enterprises
Objective To describe the pattern of development of incidence of multiple sclerosis (MS)
over 60 years in Denmark with age-period-cohort analyses and seasonality of birth. Methods …

[HTML][HTML] Differential diagnosis of multiple sclerosis and other inflammatory CNS diseases

P Wildner, M Stasiołek, M Matysiak - Multiple sclerosis and related …, 2020 - Elsevier
Multiple sclerosis (MS) is the most common acquired demyelinating disorder of the central
nervous system (CNS). Diagnosing MS can be very challenging owing to its variable clinical …

Infection as an environmental trigger of multiple sclerosis disease exacerbation

AJ Steelman - Frontiers in immunology, 2015 - frontiersin.org
Over the past several decades, significant advances have been made in identifying factors
that contribute to the pathogenesis of multiple sclerosis (MS) and have culminated in the …

Age and the risks of high-efficacy disease modifying drugs in multiple sclerosis

F Schweitzer, S Laurent, GR Fink… - Current opinion in …, 2019 - journals.lww.com
Age and the risks of high-efficacy disease modifying drugs i... : Current Opinion in
Neurology Age and the risks of high-efficacy disease modifying drugs in multiple sclerosis …

Age-period-cohort analysis of the incidence of multiple sclerosis over twenty years in Lorraine, France

B Gbaguidi, F Guillemin, M Soudant, M Debouverie… - Scientific Reports, 2022 - nature.com
Multiple sclerosis (MS) is a neurodegenerative disease of the central nervous system. An
increase in MS incidence over time is reported in several regions of the world. We aimed to …

Multiple sclerosis: emerging epidemiological trends and redefining the clinical course

E Portaccio, M Magyari, EK Havrdova… - The Lancet Regional …, 2024 - thelancet.com
Multiple sclerosis is a chronic, inflammatory, and neurodegenerative disease of the central
nervous system and a major cause of neurological disability in young adults. Its prevalence …

Suicidal ideation, anxiety, and depression in patients with multiple sclerosis

CB Tauil, TC Grippe, RM Dias… - Arquivos de neuro …, 2018 - SciELO Brasil
Psychiatric disorders frequently occur in patients with multiple sclerosis (MS); however,
limited reports are available on these comorbidities. We aimed to investigate the …