Richter Transformation (RT) is the phenomenon of progression from Chronic Lymphocytic
Leukemia (CLL) into an aggressive Large-Cell Lymphoma and is typically characterized by …

Благодаря пониманию молекулярно-биологических основ патогенеза хронического
лимфолейкоза (хлл) и распределению больных в группы риска к настоящему времени …

B‐cell lymphomas are neoplastic proliferations of clonal B lymphocytes. Clonality is
generally determined by PCR amplification of VDJ rearrangements in the IgH heavy chain or …

Richter transformation (RT) is defined as the evolution of chronic lymphocytic leukemia/small
lymphocytic lymphoma (CLL/SLL) into an aggressive lymphoma. Occurring mostly in elderly …

Richter Syndrome Page 1 LYMPHOMAS (MR SMITH, SECTION EDITOR) Richter Syndrome
Adalgisa Condoluci1,2 & Davide Rossi1,2 Accepted: 17 December 2020 © The Author(s) 2021 …

Understanding the molecular biological basis of chronic lymphocytic leukemia (CLL)
pathogenesis and stratification of patients into risk groups has now led to significant …

Background Transformed lymphoma occurs when indolent lymphoma transforms into more
aggressive lymphoma usually associated with poor prognosis. Methods In this study, we …

Richter syndrome (RS) represents an aggressive transformation, most typically to diffuse
large B-cell lymphoma (DLBCL), from chronic lymphocytic leukaemia (CLL). 1, 2 The …

Background: For patients with Richter's Syndrome (RS), a durable response is rarely
achieved with standard therapies. Significant efforts have focused on the development of …

BACKGROUND Measurable residual disease (MRD) has shown to be a successful tool to
predict the outcome of patients with chronic lymphocytic leukemia (CLL), but according to …