[HTML][HTML] Genome-wide case-only analysis of gene-gene interactions with known Parkinson's disease risk variants reveals link between LRRK2 and SYT10

M Aleknonytė-Resch, J Trinh, H Leonard… - npj Parkinson's …, 2023 - nature.com
The effects of one genetic factor upon Parkinson's disease (PD) risk may be modified by
other genetic factors. Such gene-gene interaction (G× G) could explain some of the 'missing …

[HTML][HTML] The effect of FTO gene rs9939609 polymorphism on the association between colorectal cancer and different types of dietary fat intake: a case-control study

A Hajipour, NH Ardekanizadeh, Z Roumi… - Journal of Physiological …, 2023 - Springer
Background Colorectal cancer (CRC) is one of the most common cancers in the world.
Some dietary factors such as fat intake have been identified as the risk factors for CRC. This …

[HTML][HTML] An alternative method of SNP inclusion to develop a generalized polygenic risk score analysis across Alzheimer's disease cohorts

KJ Brookes, T Guetta-Baranes, A Thomas… - Frontiers in …, 2023 - frontiersin.org
Introduction Polygenic risk scores (PRSs) have great clinical potential for detecting late-
onset diseases such as Alzheimer's disease (AD), allowing the identification of those most at …