Despite recent advancements in the development of catalytic asymmetric electrophile
induced lactonization reactions of olefinic carboxylic acids, the archetypical …

Catalyst optimization processes typically rely on inductive and qualitative assumptions of
chemists based on screening data. While machine learning models using molecular …

The catalytic and enantioselective construction of quaternary (all-carbon substituents)
stereocenters poses a formidable challenge in organic synthesis due to the hindrance …

The use of synergistic catalytic strategy can usually circumvent the intrinsic limitations of one
catalytic system. In this communication, we disclose a cooperative catalysis strategy of …

The formation of Brønsted acid aggregates in the course of asymmetric organocatalytic
reactions is often overlooked in mechanistic studies, even though it might have a deep …

The conceptually designed imidodiphosphorimidates (IDPis) have emerged as one of the
most potent classes of chiral acid catalysts. They are characterized by enzyme‐like, highly …

Covering: January to the end of December 2022This review covers the literature published
in 2022 for marine natural products (MNPs), with 645 citations (633 for the period January to …

Asymmetric olefin isomerization has become a powerful tool for positional migration of C= C
double bonds to afford valuable chiral olefins. However, the synthesis of optically active all …

Spirocarbocyclic natural products have been attracting considerable attention from synthetic
organic chemists. This review focused on total syntheses of sesquiterpenoids involving spiro …

The prereactive intermediate in the furan-maleic anhydride cycloaddition, a classical Diels–
Alder reaction, has been captured and characterized in pulsed jets by Fourier transform …