The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity
Y Xiong, BB Mi, Z Lin, YQ Hu, L Yu, KK Zha… - Military Medical …, 2022 - Springer
Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …
a variety of cell types, whose activity and interplay must be precisely mediated for effective …
Knee osteoarthritis: epidemiology, pathogenesis, and mesenchymal stem cells: what else is new? An update
R Giorgino, D Albano, S Fusco, GM Peretti… - International journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is a chronic disease and the most common orthopedic disorder. A vast
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …
Recent updates of diagnosis, pathophysiology, and treatment on osteoarthritis of the knee
S Jang, K Lee, JH Ju - International journal of molecular sciences, 2021 - mdpi.com
Osteoarthritis (OA) is a degenerative and chronic joint disease characterized by clinical
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …
Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics
MS Nestor, G Ablon, A Gade, H Han… - Journal of cosmetic …, 2021 - Wiley Online Library
Background Androgenetic alopecia (AGA) is the most common form of hair loss consisting of
a characteristic receding frontal hairline in men and diffuse hair thinning in women, with …
a characteristic receding frontal hairline in men and diffuse hair thinning in women, with …
A brief overview of global trends in MSC-based cell therapy
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …
Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
C Zhou, B Zhang, Y Yang, Q Jiang, T Li, J Gong… - Stem cell research & …, 2023 - Springer
Wound healing is a dynamic and highly sequential process involving a series of overlapping
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …
Synchronous disintegration of ferroptosis defense axis via engineered exosome‐conjugated magnetic nanoparticles for glioblastoma therapy
B Li, X Chen, W Qiu, R Zhao, J Duan… - Advanced …, 2022 - Wiley Online Library
Glioblastoma (GBM) is one of the most fatal central nervous system tumors and lacks
effective or sufficient therapies. Ferroptosis is a newly discovered method of programmed …
effective or sufficient therapies. Ferroptosis is a newly discovered method of programmed …
High-quality milk exosomes as oral drug delivery system
J Zhong, B Xia, S Shan, A Zheng, S Zhang, J Chen… - Biomaterials, 2021 - Elsevier
Many drugs must be administered intravenously instead of oral administration due to their
poor oral bioavailability. The cost of repeated infusion treatment for 6 weeks every year is as …
poor oral bioavailability. The cost of repeated infusion treatment for 6 weeks every year is as …
Differential therapeutic effect of extracellular vesicles derived by bone marrow and adipose mesenchymal stem cells on wound healing of diabetic ulcers and …
Extracellular vesicles (EVs) derived from mesenchymal stem cells isolated from both bone
marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic effects. These …
marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic effects. These …
Mesenchymal stromal cell-based therapy for cartilage regeneration in knee osteoarthritis
Osteoarthritis, as a degenerative disease, is a common problem and results in high
socioeconomic costs and rates of disability. The most commonly affected joint is the knee …
socioeconomic costs and rates of disability. The most commonly affected joint is the knee …