[HTML][HTML] Monocytes and macrophages as viral targets and reservoirs

E Nikitina, I Larionova, E Choinzonov… - International journal of …, 2018 - mdpi.com
Viruses manipulate cell biology to utilize monocytes/macrophages as vessels for
dissemination, long-term persistence within tissues and virus replication. Viruses enter cells …

Understanding the regulation of “Don't Eat-Me” signals by inflammatory signaling pathways in the tumor microenvironment for more effective therapy

AZ Karizak, Z Salmasi, SM Gheibihayat… - Journal of Cancer …, 2023 - Springer
Introduction Receptor/ligand pair immune checkpoints are inhibitors that regulate immunity
as vital “Don't Find-Me” signals to the adaptive immune system, additionally, the essential …

Targeted delivery of a phosphoinositide 3‐kinase γ inhibitor to restore organ function in sepsis

AT Press, P Babic, B Hoffmann, T Müller… - EMBO Molecular …, 2021 - embopress.org
Jaundice, the clinical hallmark of infection‐associated liver dysfunction, reflects altered
membrane organization of the canalicular pole of hepatocytes and portends poor outcomes …

[HTML][HTML] Deciphering the crosstalk of immune dysregulation between COVID-19 and idiopathic inflammatory myopathy

Z Zhang, W Tao, D Cheng, M Qin, J Fu… - Frontiers in …, 2023 - frontiersin.org
Background The coronavirus disease (COVID-19) pandemic is a serious threat to public
health worldwide. Growing evidence reveals that there are certain links between COVID-19 …

[HTML][HTML] Dose-Dependent Effects in Plasma Oncotherapy: Critical In Vivo Immune Responses Missed by In Vitro Studies

Y He, F Gong, T Jin, Q Liu, H Fang, Y Chen, G Wang… - Biomolecules, 2023 - mdpi.com
Cold atmospheric plasma (CAP) generates abundant reactive oxygen and nitrogen species
(ROS and RNS, respectively) which can induce apoptosis, necrosis, and other biological …

Regulatory T cells promote myositis and muscle damage in Toxoplasma gondii infection

RM Jin, SJ Blair, J Warunek, RR Heffner… - The Journal of …, 2017 - journals.aai.org
The coordination of macrophage polarization is essential for the robust regenerative
potential of skeletal muscle. Repair begins with a phase mediated by inflammatory …

[HTML][HTML] Discovery and replication of a peripheral tissue DNA methylation biosignature to augment a suicide prediction model

ML Clive, MP Boks, CH Vinkers, LM Osborne… - Clinical …, 2016 - Springer
Background Suicide is the second leading cause of death among adolescents in the USA,
and rates are rising. Methods to identify individuals at risk are essential for implementing …

[HTML][HTML] CD47 as a potential target to therapy for infectious diseases

LB Cham, T Adomati, F Li, M Ali, KS Lang - Antibodies, 2020 - mdpi.com
The integrin associated protein (CD47) is a widely and moderately expressed glycoprotein
in all healthy cells. Cancer cells are known to induce increased CD47 expression. Similar to …

Selective MMP-9 Inhibitor (R)-ND-336 Alone or in Combination with Linezolid Accelerates Wound Healing in Infected Diabetic Mice

Z Peng, TT Nguyen, W Song, B Anderson… - ACS Pharmacology & …, 2020 - ACS Publications
Diabetic foot ulcers (DFUs) are a common complication of diabetes that are recalcitrant to
healing due to persistent inflammation. The majority of DFUs have bacterial biofilms, with …

Protein tyrosine phosphatase SHP-1: resurgence as new drug target for human autoimmune disorders

Y Sharma, S Bashir, P Bhardwaj, A Ahmad… - Immunologic …, 2016 - Springer
Recognition of self-antigen and its destruction by the immune system is the hallmark of
autoimmune diseases. During the developmental stages, immune cells are introduced to the …