[HTML][HTML] Waiting for the truth: is reluctance in accepting an early origin hypothesis for SARS-CoV-2 delaying our understanding of viral emergence?

M Canuti, S Bianchi, O Kolbl, SLK Pond, S Kumar… - BMJ Global …, 2022 - gh.bmj.com
Two years after the start of the COVID-19 pandemic, key questions about the emergence of
its aetiological agent (SARS-CoV-2) remain a matter of considerable debate. Identifying …

The first three waves of the Covid-19 pandemic hint at a limited genetic repertoire for SARS-CoV-2

TM Wassenaar, V Wanchai, G Buzard… - FEMS Microbiology …, 2022 - academic.oup.com
The genomic diversity of SARS-CoV-2 is the result of a relatively low level of spontaneous
mutations introduced during viral replication. With millions of SARS-CoV-2 genome …

An evolutionary portrait of the progenitor SARS-CoV-2 and its dominant offshoots in COVID-19 pandemic

S Kumar, Q Tao, S Weaver… - Molecular Biology …, 2021 - academic.oup.com
Global sequencing of genomes of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has continued to reveal new genetic variants that are the key to unraveling its early …

CoVEffect: interactive system for mining the effects of SARS-CoV-2 mutations and variants based on deep learning

G Serna García, R Al Khalaf, F Invernici, S Ceri… - …, 2023 - academic.oup.com
Abstract Background Literature about SARS-CoV-2 widely discusses the effects of variations
that have spread in the past 3 years. Such information is dispersed in the texts of several …

[HTML][HTML] Data-driven analysis of amino acid change dynamics timely reveals SARS-CoV-2 variant emergence

A Bernasconi, L Mari, R Casagrandi, S Ceri - Scientific Reports, 2021 - nature.com
Since its emergence in late 2019, the diffusion of SARS-CoV-2 is associated with the
evolution of its viral genome. The co-occurrence of specific amino acid changes, collectively …

[HTML][HTML] Detection of a-to-i rna editing in sars-cov-2

E Picardi, L Mansi, G Pesole - Genes, 2021 - mdpi.com
ADAR1-mediated deamination of adenosines in long double-stranded RNAs plays an
important role in modulating the innate immune response. However, recent investigations …

[HTML][HTML] Molecular evidence for SARS-CoV-2 in samples collected from patients with morbilliform eruptions since late 2019 in Lombardy, northern Italy

A Amendola, M Canuti, S Bianchi, S Kumar… - Environmental …, 2022 - Elsevier
As a reference laboratory for measles and rubella surveillance in Lombardy, we evaluated
the association between SARS-CoV-2 infection and measles-like syndromes, providing …

[HTML][HTML] No species-level losses of s2m suggests critical role in replication of SARS-related coronaviruses

C Gilbert, T Tengs - Scientific reports, 2021 - nature.com
The genetic element s2m has been acquired through horizontal transfer by many distantly
related viruses, including the SARS-related coronaviruses. Here we show that s2m is …

[HTML][HTML] Pathogenic mechanism and multi-omics analysis of oral manifestations in COVID-19

M Hao, D Wang, Q Xia, S Kan, L Chang, H Liu… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease that seriously
threatens human life. The clinical manifestations of severe COVID-19 include acute …

ViruClust: direct comparison of SARS-CoV-2 genomes and genetic variants in space and time

L Cilibrasi, P Pinoli, A Bernasconi, A Canakoglu… - …, 2022 - academic.oup.com
Motivation The ongoing evolution of SARS-CoV-2 and the rapid emergence of variants of
concern at distinct geographic locations have relevant implications for the implementation of …