Immunologically mediated drug reactions have been traditionally classified as unpredictable
based on the fact that they cannot be predicted strictly on the pharmacological action of the …

The association of HLA-B27 with ankylosing spondylitis, a chronic inflammatory disease of
the axial skeleton, and other spondyloarthropathies, is among the strongest of an MHC …

The basis for strong immunogenetic associations between particular human leukocyte
antigen (HLA) class I allotypes and inflammatory conditions like Behçet's disease (HLA-B51) …

Objective The association of HLA–B27 with spondyloarthropathy is one of the strongest
documented for any autoimmune disease. A common hypothesis for this association is the …

The association of ERAP1 with ankylosing spondylitis (AS) 1 1The abbreviations used are:
ASankylosing spondylitisERendoplasmic reticulumERAPendoplasmic reticulum …

The association of autoimmune diseases with HLA has been known for many decades. To
date, however, the underlying mechanisms have not been fully understood. The recently …

Expression of HLA-B27 is strongly associated with ankylosing spondylitis (AS) and other
spondyloarthropathies. While this is true for the majority of HLA-B27 allotypes, HLA-B* 27 …

HLA-B27 represents a family of 38 closely related cell surface proteins (encoded by the
alleles HLA-B* 2701-39) called subtypes of HLA-B27, most of which have evolved from the …

The association of human leukocyte antigen (HLA)‐B27 to ankylosing spondylitis is one of
the strongest between a major histocompatibility complex molecule and a disease. Yet, the …

HLA-B27 is strongly associated with ankylosing spondylitis (AS). We analyzed the
relationship between structure, peptide specificity, folding, and stability of the seven major …