Current use of high-resolution mass spectrometry in drug screening relevant to clinical and forensic toxicology and doping control

I Ojanperä, M Kolmonen, A Pelander - Analytical and bioanalytical …, 2012 - Springer
Clinical and forensic toxicology and doping control deal with hundreds or thousands of
drugs that may cause poisoning or are abused, are illicit, or are prohibited in sports. Rapid …

Automated mass spectral deconvolution and identification system for GC-MS screening for drugs, poisons, and metabolites in urine

MR Meyer, FT Peters, HH Maurer - Clinical chemistry, 2010 - academic.oup.com
Background: The challenge in systematic toxicological analysis using gas chromatography
and/or liquid chromatography coupled to mass spectrometry is to identify compounds of …

Analytical toxicology

HH Maurer - … , Clinical and Environmental Toxicology: Volume 2 …, 2010 - Springer
This paper reviews procedures for screening, identification and quantification of drugs,
poisons and their metabolites in biosamples, and the corresponding work-up procedures …

Fatal toxicity index of medicinal drugs based on a comprehensive toxicology database

I Ojanperä, P Kriikku, E Vuori - International journal of legal medicine, 2016 - Springer
The fatal toxicity index (FTI) is the absolute number of fatal poisonings caused by a particular
drug divided by its consumption figure. Consequently, it is a useful measure in evaluating …

Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) procedure for screening of urine specimens for 100 analytes relevant …

D Remane, D Wetzel, FT Peters - Analytical and bioanalytical chemistry, 2014 - Springer
In recent years, drug-facilitated crime (DFC) has become an increasing problem. A minimum
list of 80 analytes to be monitored in such cases has been proposed by the Society of …

Comparison between drug screening by immunoassay and ultra‐high performance liquid chromatography/high‐resolution time‐of‐flight mass spectrometry in post …

M Sundström, A Pelander… - Drug testing and …, 2015 - Wiley Online Library
Immunoassay is currently the most common approach for urine drug screening. However,
the continuous emergence of new psychoactive substances (NPS) and their low urinary …

Performance of three point-of-care urinalysis test devices for drugs of abuse and therapeutic drugs applied in the emergency department

ME Attema-de Jonge, SYG Peeters… - The Journal of emergency …, 2012 - Elsevier
BACKGROUND: Point-of-care tests for toxicological screening of patients for drugs of abuse
and therapeutic drugs may be helpful in the emergency department (ED) to assist in a rapid …

Fast GC-MS method for the simultaneous screening of THC-COOH, cocaine, opiates and analogues including buprenorphine and fentanyl, and their metabolites in …

S Strano-Rossi, AM Bermejo, X De La Torre… - Analytical and …, 2011 - Springer
A fast gas chromatography (GC)-MS method has been developed and validated for the
simultaneous screening of different classes of drugs of abuse in urine …

A prospective cohort study of trends in self‐poisoning, Newcastle, Australia, 1987–2012: plus ça change, plus c'est la même chose

NA Buckley, IM Whyte, AH Dawson… - Medical journal of …, 2015 - Wiley Online Library
Objective: To examine inhospital mortality and morbidity associated with self‐poisoning with
different drug classes over an extended period. Design, setting and participants: A …

Rapid analysis of drugs of abuse and their metabolites in human urine using dilute and shoot liquid chromatography–tandem mass spectrometry

TY Kong, JH Kim, JY Kim, MK In, KH Choi… - Archives of pharmacal …, 2017 - Springer
Liquid chromatography-tandem mass spectrometric method for analysis of 113 abuse drugs
and their metabolites in human urine was developed and validated. A simple sample clean …