[HTML][HTML] Clinical value of drugs of abuse point of care testing in an emergency department setting

PS Lager, ME Attema-de Jonge, MP Gorzeman… - Toxicology reports, 2018 - Elsevier
Objective Toxicology screening tests for drugs-of-abuse and therapeutic drugs in urine (TST-
U) are often used to assess whether a patient's clinical condition can be explained by the …

The antipsychotic story: changes in prescriptions and overdose without better safety

I Berling, NA Buckley, GK Isbister - British journal of clinical …, 2016 - Wiley Online Library
Aims Morbidity and mortality from drug overdose has decreased over three decades. This is
credited to safer drugs and therefore better outcomes in overdose. We aimed to investigate …

Laboratory and clinical evaluation of on-site urine drug testing

O Beck, S Carlsson, M Tusic, R Olsson… - … Journal of Clinical …, 2014 - Taylor & Francis
Aim. Products for on-site urine drug testing offer the possibility to perform screening for drugs
of abuse directly at the point-of-care. This is a well-established routine in emergency and …

[HTML][HTML] Buyer beware: pitfalls in toxicology laboratory testing

DA Algren, MR Christian - Missouri Medicine, 2015 - ncbi.nlm.nih.gov
Urine drug screens are commonly used in various clinical settings and situations.
Immunoassays are the most commonly available method of testing for urine drug screens in …

Toxicology in the critical care unit

PM Alapat, JL Zimmerman - Chest, 2008 - Elsevier
Toxicologic conditions are encountered in critically ill patients due to intentional or
unintentional misuse of or exposure to therapeutic or illicit drugs. Additionally, toxicities …

Association between Prescribing and Intoxication Rates for Selected Psychotropic Drugs: A Longitudinal Observational Study

M Dobravc Verbič, I Grabnar, M Brvar - Pharmaceuticals, 2024 - mdpi.com
Psychotropic prescription drugs are commonly involved in intoxication events. The study's
aim was to determine a comparative risk for intoxication in relation to prescribing rates for …

A systematic comparison of four different workup procedures for systematic toxicological analysis of urine samples using gas chromatography–mass spectrometry

FT Peters, O Drvarov, S Lottner, A Spellmeier… - Analytical and …, 2009 - Springer
Sample preparation for systematic toxicological screening analysis (STA) in urine by gas
chromatography–mass spectrometry (GC-MS) generally involves cleavage of conjugates by …

Disposable microfluidic device with ultraviolet detection for highly resolved screening of illicit drugs

W Qiang, C Zhai, J Lei, C Song, D Zhang, J Sheng… - Analyst, 2009 - pubs.rsc.org
A disposable microfluidic device was constructed by conveniently integrating one poly
(methyl methacrylate) board with four reservoirs and one fractured fused-silica capillary with …

Central nervous system toxicity

AM Ruha, M Levine - Emergency Medicine Clinics, 2014 - emed.theclinics.com
Central nervous system (CNS) toxicity may result from exposure to a vast array of
xenobiotics. The term xenobiotic describes any substance that is foreign to the human body …

Do rapid comprehensive urine drug screens change clinical management in children?

MR Christian, JA Lowry, DA Algren, SL Thornton… - Clinical …, 2017 - Taylor & Francis
Context: Multiple studies have concluded that urine drug screens rarely change clinical
management. The rapid comprehensive urine drug screen (RCUDS) at our institution …