Uric acid participating in female reproductive disorders: a review

J Hu, W Xu, H Yang, L Mu - Reproductive Biology and Endocrinology, 2021 - Springer
Uric acid (UA) is the end metabolic product of purine metabolism. Early on, UA was
considered to be a metabolite with a certain antioxidant capacity. As research has …

Purinergic signalling in the reproductive system in health and disease

G Burnstock - Purinergic signalling, 2014 - Springer
There are multiple roles for purinergic signalling in both male and female reproductive
organs. ATP, released as a cotransmitter with noradrenaline from sympathetic nerves …

Serum uric acid in relation to endogenous reproductive hormones during the menstrual cycle: findings from the BioCycle study

SL Mumford, SS Dasharathy, AZ Pollack… - Human …, 2013 - academic.oup.com
STUDY QUESTION Do uric acid levels across the menstrual cycle show associations with
endogenous estradiol (E2) and reproductive hormone concentrations in regularly …

Association between the prevalence of hyperuricemia and reproductive hormones in polycystic ovary syndrome

L Mu, J Pan, L Yang, Q Chen, Y Chen, Y Teng… - Reproductive Biology …, 2018 - Springer
Background The prevalecne of hyperuricemia in polycystic ovary syndrome (PCOS) is still
uncertain. We aimed to investigate the prevalence of hyperuricemia in PCOS and to …

Equine maternal aging affects the metabolomic profile of oocytes and follicular cells during different maturation time points

GD Catandi, DR Bresnahan, SO Peters… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Oocyte quality and fertility decline with advanced maternal age. During
maturation within the ovarian follicle, the oocyte relies on the associated somatic cells …

Elevated serum uric acid is associated with infertility in women living in America

X Hong, F Zhao, W Wang, J Wu, X Zhu, B Wang - Scientific Reports, 2023 - nature.com
Excessive uric acid levels may affect several organs and systems in the body. There is
limited evidence of the effects of high serum uric acid levels on the female reproductive …

Implications of serum uric acid for female infertility: results from the national health and nutrition examination survey, 2013–2020

J Liang, X Chen, J Huang, W Nie, Q Yang, Q Huang… - BMC women's …, 2023 - Springer
Background There is limited concrete evidence connecting serum uric acid levels to female
infertility. Therefore, this study aimed to find out if serum uric acid levels are independently …

Maturation and culture affect the metabolomic profile of oocytes and follicular cells in young and old mares

DR Bresnahan, GD Catandi, SO Peters… - Frontiers in Cell and …, 2024 - frontiersin.org
Introduction: Oocytes and follicular somatic cells within the ovarian follicle are altered during
maturation and after exposure to culture in vitro. In the present study, we used a nontargeted …

Nontargeted metabolomics analysis of follicular fluid in patients with endometriosis provides a new direction for the study of oocyte quality

Y Wei, Z Zhang, Y Zhang, J Li, X Ruan, Q Wan… - …, 2023 - Wiley Online Library
Endometriosis is a common, estrogen‐dependent chronic gynecological disease that
endangers the reproductive system and systemic metabolism of patients. We aimed to …

A comparative study on oxidative and antioxidative markers of serum and follicular fluid in GnRH agonist and antagonist cycles

E Celik, O Celik, B Kumbak, E Yilmaz… - Journal of assisted …, 2012 - Springer
Objective To determine whether concentrations of oxidative stress markers of follicular fluid
and serum are different in GnRH agonist protocol from GnRH antagonist protocol. Material …