[HTML][HTML] USP5: Comprehensive insights into structure, function, biological and disease-related implications, and emerging therapeutic opportunities
ST Gao, X Xin, Z Wang, Y Hu, Q Feng - Molecular and Cellular Probes, 2024 - Elsevier
Abstract Ubiquitin specific protease 5 (USP5) is a vital deubiquitinating enzyme that
regulates various physiological functions by removing ubiquitin chains from target proteins …
regulates various physiological functions by removing ubiquitin chains from target proteins …
[HTML][HTML] The E3 ligase TRIM26 suppresses ferroptosis through catalyzing K63-linked ubiquitination of GPX4 in glioma
Z Wang, Y Xia, Y Wang, R Zhu, H Li, Y Liu… - Cell Death & …, 2023 - nature.com
The selenium-containing enzyme GPX4 moonlights as a central regulator of ferroptosis, an
iron-dependent, nonapoptotic form of regulated cell death caused by lipid peroxidation. Yet …
iron-dependent, nonapoptotic form of regulated cell death caused by lipid peroxidation. Yet …
[HTML][HTML] Roles of post-translational modifications of UHRF1 in cancer
L Gu, Y Fu, X Li - Epigenetics & Chromatin, 2024 - Springer
UHRF1 as a member of RING-finger type E3 ubiquitin ligases family, is an epigenetic
regulator with five structural domains. It has been involved in the regulation of a series of …
regulator with five structural domains. It has been involved in the regulation of a series of …
[HTML][HTML] The AEG-1-USP10-PARP1 axis confers radioresistance in esophageal squamous cell carcinoma via facilitating homologous recombination-dependent DNA …
X Zhao, Y Ma, J Li, X Sun, Y Sun, F Qu, X Shi, Y Xie… - Cancer letters, 2023 - Elsevier
Radiotherapy is the standard adjuvant treatment for esophageal squamous cell carcinoma
(ESCC), yet radioresistance remains a major obstacle leading to treatment failure and …
(ESCC), yet radioresistance remains a major obstacle leading to treatment failure and …
[HTML][HTML] UCHL1 promotes the proliferation of porcine granulosa cells by stabilizing CCNB1
S Shi, H Yuan, L Zhang, L Gao, L Zhao, X Zeng… - Journal of Animal …, 2024 - Springer
Background The proliferation of porcine ovarian granulosa cells (GCs) is essential to
follicular development and the ubiquitin–proteasome system is necessary for maintaining …
follicular development and the ubiquitin–proteasome system is necessary for maintaining …
Using Förster Resonance Energy Transfer (FRET) to Understand the Ubiquitination Landscape
JK Gill, GS Shaw - ChemBioChem, 2024 - Wiley Online Library
Förster resonance energy transfer (FRET) is a fluorescence technique that allows
quantitative measurement of protein interactions, kinetics and dynamics. This review covers …
quantitative measurement of protein interactions, kinetics and dynamics. This review covers …