IL-17 and IL-17-producing cells in protection versus pathology
KHG Mills - Nature Reviews Immunology, 2023 - nature.com
IL-17 cytokine family members have diverse biological functions, promoting protective
immunity against many pathogens but also driving inflammatory pathology during infection …
immunity against many pathogens but also driving inflammatory pathology during infection …
Host–pathogen interaction in leishmaniasis: immune response and vaccination strategies
Leishmaniasis is a zoonotic and vector-borne infectious disease that is caused by the genus
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …
Regulatory T cells control Staphylococcus aureus and disease severity of cutaneous leishmaniasis
TP Singh, C Farias Amorim, VM Lovins… - Journal of Experimental …, 2023 - rupress.org
Cutaneous leishmaniasis causes alterations in the skin microbiota, leading to pathologic
immune responses and delayed healing. However, it is not known how these microbiota …
immune responses and delayed healing. However, it is not known how these microbiota …
Leishmaniasis: immune cells crosstalk in macrophage polarization
FS Almeida, SER Vanderley, FC Comberlang… - Tropical Medicine and …, 2023 - mdpi.com
Leishmaniasis is a complex infectious parasitic disease caused by protozoa of the genus
Leishmania, belonging to a group of neglected tropical diseases. It establishes significant …
Leishmania, belonging to a group of neglected tropical diseases. It establishes significant …
Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation
Although early life colonization of commensal microbes contributes to long-lasting immune
imprinting in host tissues, little is known regarding the pathophysiological consequences of …
imprinting in host tissues, little is known regarding the pathophysiological consequences of …
Eosinophils, but Not Type 2 Innate Lymphoid Cells, Are the Predominant Source of Interleukin 4 during the Innate Phase of Leishmania major Infection
C Sasse, D Barinberg, S Obermeyer, A Debus… - Pathogens, 2022 - mdpi.com
Interleukin (IL)-4 plays a central role in the initiation of a type 2 T helper cell (Th2) response,
which leads to non-healing and progressive infections with the protozoan parasite …
which leads to non-healing and progressive infections with the protozoan parasite …
CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions
L Amorim Sacramento, C Farias Amorim… - Plos …, 2024 - journals.plos.org
Cytolytic CD8+ T cells mediate immunopathology in cutaneous leishmaniasis without
controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion …
controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion …
Central and Effector Memory Human CD4+ and CD8+ T Cells during Cutaneous Leishmaniasis and after In Vitro Stimulation with Leishmania (Viannia) braziliensis …
BC de Oliveira, AA da Silva… - Vaccines, 2023 - mdpi.com
Cutaneous Leishmaniasis (CL) is a Neglected Tropical Disease characterized by skin ulcers
caused by Leishmania spp. protozoans and there is no safe and effective vaccine to reduce …
caused by Leishmania spp. protozoans and there is no safe and effective vaccine to reduce …
CD1d‐Dependent Natural Killer T Cells Mediate Hypertension and Vascular Injury Through Interleukin‐17A
X Xiao, CL Hou, YL Zhang, H Yang… - Journal of the …, 2023 - Am Heart Assoc
Background Different T‐lymphocyte subsets, including CD1d‐dependent natural killer T
(NKT) cells, play distinct roles in hypertension, highlighting the importance of identifying key …
(NKT) cells, play distinct roles in hypertension, highlighting the importance of identifying key …
Prokaryotic and eukaryotic skin microbiota modifications triggered by Leishmania infection in localized Cutaneous Leishmaniasis
J Jaimes, LH Patiño, G Herrera, C Cruz… - PLOS Neglected …, 2024 - journals.plos.org
Cutaneous Leishmaniasis (CL) is a tropical disease characterized by cutaneous ulcers,
sometimes with satellite lesions and nodular lymphangitis. Leishmania parasites …
sometimes with satellite lesions and nodular lymphangitis. Leishmania parasites …