Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp3)–H Bonds

B Liu, AM Romine, CZ Rubel, KM Engle… - Chemical reviews, 2021 - ACS Publications
Transition-metal-catalyzed, coordination-assisted C (sp3)–H functionalization has
revolutionized synthetic planning over the past few decades as the use of these directing …

3d transition metals for C–H activation

P Gandeepan, T Müller, D Zell, G Cera… - Chemical …, 2018 - ACS Publications
C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …

Manganese-Catalyzed Oxidative Azidation of C(sp3)–H Bonds under Electrophotocatalytic Conditions

L Niu, C Jiang, Y Liang, D Liu, F Bu, R Shi… - Journal of the …, 2020 - ACS Publications
The selective installation of azide groups into C (sp3)–H bonds is a priority research topic in
organic synthesis, particularly in pharmaceutical discovery and late-stage diversification …

Transition metal-catalyzed C–H amination: scope, mechanism, and applications

Y Park, Y Kim, S Chang - Chemical reviews, 2017 - ACS Publications
Catalytic transformation of ubiquitous C–H bonds into valuable C–N bonds offers an efficient
synthetic approach to construct N-functionalized molecules. Over the last few decades …

Zr-based metal–organic frameworks: design, synthesis, structure, and applications

Y Bai, Y Dou, LH Xie, W Rutledge, JR Li… - Chemical Society …, 2016 - pubs.rsc.org
Among the large family of metal–organic frameworks (MOFs), Zr-based MOFs, which exhibit
rich structure types, outstanding stability, intriguing properties and functions, are foreseen as …

Mild metal-catalyzed C–H activation: examples and concepts

T Gensch, MN Hopkinson, F Glorius… - Chemical Society …, 2016 - pubs.rsc.org
Organic reactions that involve the direct functionalization of non-activated C–H bonds
represent an attractive class of transformations which maximize atom-and step-economy …

Advances in synthetic applications of hypervalent iodine compounds

A Yoshimura, VV Zhdankin - Chemical reviews, 2016 - ACS Publications
The preparation, structure, and chemistry of hypervalent iodine compounds are reviewed
with emphasis on their synthetic application. Compounds of iodine possess reactivity similar …

The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

T Cernak, KD Dykstra, S Tyagarajan… - Chemical Society …, 2016 - pubs.rsc.org
The advent of modern C–H functionalization chemistries has enabled medicinal chemists to
consider a synthetic strategy, late stage functionalization (LSF), which utilizes the C–H …

Transition-metal-catalyzed C–N bond forming reactions using organic azides as the nitrogen source: a journey for the mild and versatile C–H amination

K Shin, H Kim, S Chang - Accounts of chemical research, 2015 - ACS Publications
Conspectus Owing to the prevalence of nitrogen-containing compounds in functional
materials, natural products and important pharmaceutical agents, chemists have actively …

Copper-Promoted Functionalization of Organic Molecules: from Biologically Relevant Cu/O2 Model Systems to Organometallic Transformations

R Trammell, K Rajabimoghadam… - Chemical …, 2019 - ACS Publications
Copper is one of the most abundant and less toxic transition metals. Nature takes advantage
of the bioavailability and rich redox chemistry of Cu to carry out oxygenase and oxidase …