Apathy associated with antidepressant drugs: a systematic review

VG Masdrakis, M Markianos, DS Baldwin - Acta Neuropsychiatrica, 2023 - cambridge.org
Objectives: Administration of antidepressant drugs–principally selective serotonin reuptake
inhibitors (SSRIs)–may induce clinically significant 'apathy'which can affect treatment …

Trends in antidepressant use and expenditure in six major cities in China from 2013 to 2018

Z Yu, J Zhang, Y Zheng, L Yu - Frontiers in Psychiatry, 2020 - frontiersin.org
The objective of this study was to investigate the current status and trends in antidepressant
use and expenditure in China from 2013 to 2018. The study had a retrospective design …

Methodological flaws, conflicts of interest, and scientific fallacies: implications for the evaluation of antidepressants' efficacy and harm

MP Hengartner - Frontiers in psychiatry, 2017 - frontiersin.org
Background In current psychiatric practice, antidepressants are widely and with ever-
increasing frequency prescribed to patients. However, several scientific biases obfuscate …

Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication

M Bellet, F Ahmad, R Villanueva… - Therapeutic …, 2019 - journals.sagepub.com
Drug–drug interactions are of significant concern in clinical practice in oncology, particularly
in patients receiving Cyclin-dependent kinase (CDK) 4/6 inhibitors, which are typically …

Novel therapies for glaucoma: a patent review (2013-2019)

P Guglielmi, S Carradori, C Campestre… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Glaucoma is one of the main leading causes of irreversible blindness in the
world. The treatment of this disease relies on the use of drugs able to reduce/control the …

The relationship between 5-hydroxytryptamine and its metabolite changes with post-stroke depression

S Gu, Z He, Q Xu, J Dong, T Xiao, F Liang, X Ma… - Frontiers in …, 2022 - frontiersin.org
Post-stroke depression (PSD) is the most common and serious sequelae of stroke.
Approximately 33% of stroke survivors were affected by PSD. However, many issues (eg …

The sociodemographic and clinical profile of patients with major depressive disorder receiving SSRIs as first-line antidepressant treatment in European countries

G Fugger, L Bartova, C Fabbri, G Fanelli… - European archives of …, 2022 - Springer
Introduction Due to favorable antidepressant (AD) efficacy and tolerability, selective-
serotonin reuptake inhibitors (SSRIs) are consistently recommended as substances of first …

The binding mode of vilazodone in the human serotonin transporter elucidated by ligand docking and molecular dynamics simulations

Y Zhang, G Zheng, T Fu, J Hong, F Li, X Yao… - Physical Chemistry …, 2020 - pubs.rsc.org
Vilazodone is a novel antidepressant used for the treatment of major depressive disorder
(MDD) with a primary action mechanism of inhibiting the human serotonin reuptake …

Factors related to age at depression onset: the role of SLC6A4 methylation, sex, exposure to stressful life events and personality in a sample of inpatients suffering …

S Sanwald, K Widenhorn-Müller… - BMC psychiatry, 2021 - Springer
Background An early onset of depression is associated with higher chronicity and disability,
more stressful life events (SLEs), higher negative emotionality as described by the primary …

Low doses and lifecycle exposure of waterborne antidepressants in zebrafish model: A survey on sperm traits, reproductive behaviours, and transcriptome responses

X Hong, R Chen, L Zhang, L Yan, J Li, J Zha - Science of The Total …, 2022 - Elsevier
Venlafaxine and citalopram have been commonly found in surface water and may disrupt
fish reproduction, yet the long-term impact and the underlying mechanism are largely …