Background: The purpose of this open trial was to evaluate the safety, tolerability, and
efficacy of oral S-adenosyl-l-methionine as an antidepressant adjunct among partial and …

Despite the increasingly large array of antidepressants available to treat major depressive
disorder, patients continue to experience relatively modest response and remission rates. In …

We examined the efficacy of a vitamin/nutriceutical formulation (folate, vitamin B6, alpha-
tocopherol, S-adenosyl methionine, N-acetyl cysteine, and acetyl-L-carnitine) in a 12-month …

Attention-deficit/hyperactivity disorder (ADHD) is a commonly diagnosed childhood disorder
characterized by impulsivity, inattention, and hyperactivity. ADHD affects up to 1 in 20 …

Interest in nonpharmaceutical supplements for treating major depressive disorder (MDD)
has increased significantly, both among patients and among clinicians during the past …

The polyamine pathway has an essential role in many cellular functions and has been
implicated in several pathological conditions. Accumulating evidence suggests that the …

BACKGROUND: In 2001, the Canadian Psychiatric Association and the Canadian Network
for Mood and Anxiety Treatments (CANMAT) partnered to produce evidence-based clinical …

Background Postnatal depression is a medical condition that affects many women and the
development of their infants. There is a lack of evidence for treatment and prevention …

Background Major depressive disorder (MDD) is a recurrent illness with high rates of
chronicity, treatment-resistance, and significant economic impact. S-Adenosylmethionine …

BackgroundThe use of complementary medicines in those with mental health problems is
well documented. However, their effectiveness is often not established and they may be less …