Noncompaction cardiomyopathy (NCCM) is a rare condition characterized by prominent
trabeculae, deep intertrabecular recesses, and a left ventricular myocardium with a two …

Heart failure with preserved ejection fraction (HFpEF) is a complex clinical syndrome
responsible for high mortality and morbidity rates. It has an ever growing social and …

BACKGROUND: Recommendations for apixaban dosing on the basis of kidney function are
inconsistent between the US Food and Drug Administration and European Medicines …

Oral anticoagulants (OACs) are commonly used to reduce the risk of venous
thromboembolism and the risk of stroke in patients with atrial fibrillation. Endorsed by the …

Aims Atrial fibrillation (AF) and chronic kidney disease (CKD) often coexist and share an
increased risk of thrombo-embolism (TE). CKD concomitantly predisposes towards a pro …

Background Diltiazem, a moderate cytochrome P450 3A4 isozyme/P‐glycoprotein inhibitor,
may potentiate the bleeding risk of direct oral anticoagulants (DOACs) through …

ABSTRACT Introduction Oral anticoagulants (OACs) are the cornerstone of stroke
prevention in atrial fibrillation (AF), but prescribing decisions in older people are …

Chronic kidney disease (CKD) is a major public health problem, affecting between 8% and
16% of the population worldwide [1–7]. The global burden of CKD has grown faster than that …

The frequent coexistence in daily clinical practice of chronic kidney disease (CKD) and atrial
fibrillation (AF), especially in the elderly, represents a conundrum for physicians, mainly …

Introduction Atrial fibrillation (AF) and chronic kidney disease (CKD) are closely related.
These diseases share common risk factors and are associated with increased risk of …