[HTML][HTML] Recent advances on thermosensitive hydrogels-mediated precision therapy

H Chen, J Xu, J Sun, Y Jiang, W Zheng, W Hu… - Asian Journal of …, 2024 - Elsevier
Precision therapy has become the preferred choice attributed to the optimal drug
concentration in target sites, increased therapeutic efficacy, and reduced adverse effects …

The Current Situation and Development Prospect of Whole-Genome Screening

C Yang, Y Lei, T Ren, M Yao - International Journal of Molecular Sciences, 2024 - mdpi.com
High-throughput genetic screening is useful for discovering critical genes or gene
sequences that trigger specific cell functions and/or phenotypes. Loss-of-function genetic …

Nanosynergist-engineered oncolytic adenovirus enhancing immune-virotherapy efficacy for glioblastoma via interrupting antiviral responses

J Xu, X Liu, J Ding, H Zhang, T Yao, S Li, R Yang, N Yu… - Nano Today, 2024 - Elsevier
Oncolytic adenoviruses (OA) are promising therapeutics for glioblastoma (GBM) due to their
unique capability of selectively lysing tumor cells and activating the immune response …

Exploring the potential biological significance of KDELR family genes in lung adenocarcinoma

P Li, P Cui, Q Yue, Z Xu, Z Liu - Scientific Reports, 2024 - nature.com
Abstract The Lys-Asp-Glu-Leu receptor (KDELR) family genes play critical roles in a variety
of biological processes in different tumors. Our study aimed to provide a comprehensive …

An innovative gene expression modulating strategy by converting nucleic acids into HNC therapeutics using carrier-free nanoparticles

H Liu, Y Huang, Z Li, S Han, T Liu, Q Zhao - Frontiers in Immunology, 2024 - frontiersin.org
Background Cell fate and microenvironmental changes resulting from aberrant expression
of specific proteins in tumors are one of the major causes of inadequate anti-tumor immune …