[HTML][HTML] Molecular Mechanisms Responsible for the Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Lung Fibrosis

CR Harrell, V Djonov, A Volarevic… - International journal of …, 2024 - mdpi.com
Mesenchymal stem cell-derived exosomes (MSC-Exos) are nano-sized extracellular
vesicles which contain various MSC-sourced anti-fibrotic, immunoregulatory and angio …

Unraveling the interplay between vital organelle stress and oxidative stress in idiopathic pulmonary fibrosis

A Mohanan, KR Washimkar, MN Mugale - Biochimica et Biophysica Acta …, 2024 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized
by excessive accumulation of extracellular matrix, leading to irreversible fibrosis. Emerging …

Therapeutic effects of flavonoids on pulmonary fibrosis: a preclinical meta-analysis

Q Geng, L Yan, C Shi, L Zhang, L Li, P Lu, Z Cao, X He… - Phytomedicine, 2024 - Elsevier
Background The efficacy of flavonoid supplementation in animal models of pulmonary
fibrosis has been demonstrated. Purpose We conducted a systematic review and meta …

[HTML][HTML] Aerosol delivery in interstitial lung diseases-breakthrough or lost cause?

C Ehrhardt - Expert Opinion on Drug Delivery, 2024 - Taylor & Francis
Interstitial lung diseases (ILDs) encompass a heterogeneous group of lung disorders, each
with its own etiology, clinical presentation, and progression, characterized by inflammation …

[HTML][HTML] Amentoflavone Mitigates Cyclophosphamide-Induced Pulmonary Toxicity: Involvement of-SIRT-1/Nrf2/Keap1 Axis, JAK-2/STAT-3 Signaling, and Apoptosis

MF Balaha, AA Alamer, RM Aldossari, AH Aodah… - Medicina, 2023 - mdpi.com
Background and objectives: Cyclophosphamide (CPA) is an alkylating agent that is used for
the management of various types of malignancies and as an immunosuppressive agent for …

Bexotegrast in Patients with Idiopathic Pulmonary Fibrosis: The INTEGRIS-IPF Study

L Lancaster, V Cottin, M Ramaswamy… - American Journal of …, 2024 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a rare and progressive disease, which
causes progressive cough, exertional dyspnea, impaired quality of life and death …