Incidence of oesophageal adenocarcinoma has increased exponentially in the West over
the past few decades. Following detection of advanced cancers, 5-year survival rates remain …

Barrett's esophagus (BE) is characterized by a change of the normal stratified squamous
epithelium lining the esophagus to a metaplastic columnar epithelium with goblet cells. The …

Endoscopic cryotherapy is a technique utilized for the ablation of target tissue within the
gastrointestinal tract. A cryotherapy system utilizes the endoscopic application of cryogen …

Introduction: Cryotherapy is a cold-based ablative therapy used primarily as second line
therapy in patients with Barrett's esophagus (BE) who have persistent dysplasia after …

Background Cryotherapy uses extremely cold temperatures for tissue destruction. In the GI
tract, cryotherapy can be performed using devices designed for use with endoscopes …

Endoscopic cryotherapy is a relatively new thermal ablative modality used for the treatment
of neoplastic lesions of the esophagus. It relies on cycles of rapid cooling and thawing to …

Cryotherapy, the therapeutic use of cold temperature, dates back to Egyptian time in 3000
BC. 1 In ancient times, cryotherapy was mainly used for its anti-inflammatory and anesthetic …

Endoscopic eradication therapy for Barrett's esophagus has been established as an
effective management strategy for patients with Barrett's esophagus with dysplasia and early …

The concept of cryotherapy is appealing. By preserving the extracellular matrix and inducing
anesthetic effects, cryotherapy has the potential to enable deeper ablations with less pain …

Abstract Background and Aim Liquid nitrogen cryotherapy (LNC) allows increased depth of
ablation compared with radiofrequency ablation in Barrett's esophagus (BE). Expert centers …