Inflammation is a complex and necessary component of the response to biological,
chemical, or physical stimuli, and the cellular and molecular events that initiate and regulate …

C-type lectins (CTLs) represent the most complex family of animal/human lectins that
comprises 17 different groups. During evolution, CTLs have developed by diversification to …

The mononuclear phagocyte system comprises a network of circulating monocytes and
dendritic cells (DCs), and “histiocytes”(tissue-resident macrophages and DCs) that are …

Fibrogenesis is a progressive scarring event resulting from disrupted regular wound healing
due to repeated tissue injury and can end in organ failure, like in liver cirrhosis. The …

Microgravity induces a number of significant physiological changes in the cardiovascular,
nervous, immune systems, as well as the bone tissue of astronauts. Changes in cell …

Leukocyte migration across the endothelial barrier plays an essential role in CNS
inflammation. The migration process requires complex endothelial adhesion molecules …

Carbohydrates serve as important energy sources and structural substances for human
body as well as for gut microbes. As evidenced by the advances in immunometabolism …

In the brain, cell adhesion molecules (CAMs) are critical for neurite outgrowth, axonal
fasciculation, neuronal survival and migration, and synapse formation and maintenance …

Neutrophils rolling at high shear stress (above 6 dyn/cm2) form tethers in the rear and slings
in the front. Here, we developed a novel photo-lithographically fabricated, silicone (PDMS) …

Both host defense and immunopathology are shaped by the ordered recruitment of
circulating leukocytes to affected sites, a process initiated by binding of blood-borne cells to …