By mobilizing small DNA units, integrons have a major function in the dissemination of
antibiotic resistance among bacteria. The acquisition of gene cassettes occurs by …

Misalignment of repeated sequences during DNA replication can lead to deletions or
duplications in genomic DNA. In Escherichia coli, such genetic rearrangements can occur at …

It has previously been shown that recombination between tandem repeats is not significantly
affected by a recA mutation in Escherichia coli. Here, we describe the activation of a RecA …

Duplication or expansion of directly repeated sequence elements is associated with a
number of human genetic diseases. To study the mechanisms of repeat expansion, we have …

Common laboratory strains of Bacillus subtilis encode two glutamate dehydrogenases: the
enzymatically active protein RocG and the cryptic enzyme GudB that is inactive due to a …

Certain replication mutations lead in Escherichia coli to a specific reaction named replication
fork reversal: at blocked forks, annealing of the nascent strands and pairing of the template …

RecBCD is a DNA helicase/exonuclease implicated in degradation of foreign linear DNA
and in RecA-dependent recombinational repair of chromosomal lesions in E. coli. The low …

Strand misalignments at DNA repeats during replication are implicated in mutational
hotspots. To study these events, we have generated strains carrying mutations in the …

Sensitization to cockroach allergens is associated with the development of asthma. Bla g 1
is a German cockroach allergen that shows allergenic cross‐reactivity with American …

The bacterium Deinococcus radiodurans is one of the most radioresistant organisms known.
It is able to reconstruct a functional genome from hundreds of radiation-induced …