Acinetobacter baumannii: an evolving and cunning opponent

J Shi, J Cheng, S Liu, Y Zhu, M Zhu - Frontiers in Microbiology, 2024 - frontiersin.org
Acinetobacter baumannii is one of the most common multidrug-resistant pathogens causing
nosocomial infections. The prevalence of multidrug-resistant A. baumannii infections is …

Cefiderocol and Sulbactam-Durlobactam against Carbapenem-Resistant Acinetobacter baumannii

A Karruli, A Migliaccio, S Pournaras… - Antibiotics, 2023 - mdpi.com
Infections caused by carbapenem-resistant Acinetobacter baumannii (CRAB) remain a
clinical challenge due to limited treatment options. Recently, cefiderocol, a novel …

Characterization of carbapenemase-and ESBL-Producing gram-negative Bacilli isolated from patients with urinary tract and bloodstream infections

IA Tickler, D Kawa, AE Obradovich, FC Fang… - Antibiotics, 2023 - mdpi.com
A total of 199 Gram-negative bacterial isolates from urinary tract infections and 162 from
bloodstream infections were collected from 12 healthcare systems throughout the United …

Successful Treatment of Carbapenem-Resistant Acinetobacter baumannii Meningitis With Sulbactam-Durlobactam

PD Tamma, S Immel, SM Karaba… - Clinical Infectious …, 2024 - academic.oup.com
Background The treatment of carbapenem-resistant Acinetobacter baumannii/calcoaceticus
complex (CRAB) presents significant treatment challenges. Methods We report the case of a …

Targeting the cysteine biosynthesis pathway: Mechanism, structure, and drug discovery

Y Tao, D Zheng, W Zou, T Guo, G Liao… - European Journal of …, 2024 - Elsevier
Owing to the global health crisis of resistant pathogenic infections, researchers are
emphasizing the importance of novel prevention and control strategies. Existing …

Approaches to Testing Novel β-Lactam and β-Lactam Combination Agents in the Clinical Laboratory

C Russo, R Humphries - Antibiotics, 2023 - mdpi.com
The rapid emergence of multi-drug resistant Gram-negative pathogens has driven the
introduction of novel β-lactam combination agents (BLCs) to the antibiotic market …

[HTML][HTML] New Agents Are Coming, and So Is the Resistance

JM Keck, A Viteri, J Schultz, R Fong, C Whitman… - Antibiotics, 2024 - ncbi.nlm.nih.gov
Antimicrobial resistance is a global threat that requires urgent attention to slow the spread of
resistant pathogens. The United States Centers for Disease Control and Prevention (CDC) …

Sulbactam-Durlobactam, A Novel Drug for the Treatment of Multidrug Resistant Acinetobacter baumannii Infections-A Systematic Review

H Velmurugan, S Venkatesan, HN Meles… - … Current Drug Targets …, 2024 - ingentaconnect.com
Background: Sulbactam-durlobactam (SUL-DUR) has been tested in vitro for its ability to
generate resistance in clinical isolates of Acinetobacter species. According to prior studies …

Observaciones y reflexiones durante una visita de enfermedades infecciosas

SM Montecinos, A Aguayo-Reyes… - Revista Chilena de …, 2024 - revinf.cl
La visita diaria por parte de un equipo de enfermedades infecciosas en un hospital
asistencial docente del sistema público está enfocada principalmente en el ejercicio …

Resistencia antibiótica en Acinetobacter spp. y Enterobacter cloacae complex: epidemiología, mecanismos y tratamiento

C Lasarte-Monterrubio - 2024 - ruc.udc.es
La resistencia antibiótica, con Acinetobacter baumannii y Enterobacter cloacae complex
(ECC) como microorganismos clave, constituye una causa importante de morbimortalidad a …