[HTML][HTML] Stichoposide C and Rhizochalin as Potential Aquaglyceroporin Modulators

JW Im, JH Lim, VA Stonik, JY Kwak, S Jin, M Son… - Marine Drugs, 2024 - mdpi.com
Aquaporins (AQPs) are a family of integral membrane proteins that selectively transport
water and glycerol across the cell membrane. Because AQPs are involved in a wide range …

Unraveling the Aquaporin-3 inhibitory effect of rottlerin by experimental and computational approaches

I Paccetti-Alves, MSP Batista, C Pimpão… - International Journal of …, 2023 - mdpi.com
The natural polyphenolic compound Rottlerin (RoT) showed anticancer properties in a
variety of human cancers through the inhibition of several target molecules implicated in …

[HTML][HTML] Tissue-Specific Variation in Aquaporins and Cytokines Transcriptional Profiles in Piglets being LPS Challenged

IV da Silva, D Coelho, JAM Prates, G Soveral… - Frontiers in Bioscience …, 2023 - imrpress.com
Background: Lipopolysaccharide (LPS), an effective stimulator of the immune system, has
been widely applied in an experimental pig model for human sepsis. Aquaporins (AQPs), a …

Novel therapeutic targets for organ injury and dysfunction in systemic inflammation

S Mohammad - 2022 - qmro.qmul.ac.uk
Sepsis is caused by systemic (blood) infection and is a major health concern as it is the
primary cause of death from infection. There are no specific effective treatments for sepsis …