Due to today's fast-paced lifestyle, most people are in a state of sub-health and face
“unexplained fatigue”, which can seriously affect their health, work efficiency, and quality of …

Animal models indicate that motor behaviour is shaped by monoamine neuromodulators
released diffusely throughout the brain and spinal cord. As an alternative to conducting a …

Serotonergic neuromodulation contributes to enhanced voluntary muscle activation.
However, it is not known how the likely motoneurone receptor candidate (5‐HT2) influences …

Spinal motoneuron firing depends greatly on persistent inward currents (PICs), which in turn
are facilitated by the neuromodulators serotonin and noradrenaline. The aim of this study …

This cross-sectional study examined the lower limb balance, ankle dorsiflexion, orofacial
tissue pressure, and occlusal strength of rugby players. Twenty-six participants were divided …

Serotonin modulates corticospinal excitability, motoneurone firing rates and contractile
strength via 5‐HT2 receptors. However, the effects of these receptors on cortical and …

Purpose Persistent inward calcium and sodium currents (PICs) are crucial for initiation and
maintenance of motoneuron firing, and thus muscular force. However, there is a lack of data …

HT2 receptors on motoneurones play a critical role in facilitating persistent inward currents
(PICs). Although facilitation of PICs can enhance self‐sustained firing after periods of …

The physiological mechanisms determining the progressive decline in the maximal muscle
torque production capacity during isometric contractions to task failure are known to depend …

Orexin/hypocretin terminals innervate the dorsal raphe nucleus (DRN), which projects to
motor control areas important for spontaneous physical activity (SPA) and energy …