General considerations for lung function testing

MR Miller, R Crapo, J Hankinson… - European …, 2005 - Eur Respiratory Soc
BACKGROUND⇓ In preparing the joint statements on lung function testing for the American
Thoracic Society (ATS) and the European Respiratory Society (ERS), it was agreed by the …

Pharmacokinetics and bioavailability of aerosolized tobramycin in cystic fibrosis

DE Geller, WH Pitlick, PA Nardella, WG Tracewell… - Chest, 2002 - Elsevier
Study objectives To describe the pharmacokinetics and bioavailability of inhaled tobramycin
(TOBI; Chiron Corporation; Seattle, WA), 300-mg dose, delivered by a nebulizer (PARI LC …

ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests

AL Coates, J Wanger, DW Cockcroft… - European …, 2017 - Eur Respiratory Soc
This international task force report updates general considerations for bronchial challenge
testing and the performance of the methacholine challenge test. There are notable changes …

Standardisation of spirometry

MR Miller, J Hankinson, V Brusasco… - European respiratory …, 2005 - Eur Respiratory Soc
Standardisation of spirometry | European Respiratory Society Skip to main content Main menu
Home Current issue ERJ Early View Past issues ERS Guidelines Authors/reviewers …

[图书][B] Pharmaceutical inhalation aerosol technology

AJ Hickey - 2003 - taylorfrancis.com
This thoroughly revised and expanded reference provides authoritative discussions on the
physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors …

Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator

CJ Hunter, A Dejam, AB Blood, H Shields… - Nature medicine, 2004 - nature.com
The blood anion nitrite contributes to hypoxic vasodilation through a heme-based, nitric
oxide (NO)–generating reaction with deoxyhemoglobin and potentially other heme proteins …

Particle deposition in human lung airways: effects of airflow, particle size, and mechanisms

C Ou, J Hang, Q Deng - Aerosol and Air Quality Research, 2020 - aaqr.org
Characterizing particle deposition in the airways of the human lungs is essential to evaluate
the health effects of particulate air pollution. However, lung deposition is rather complicated …

Delivery efficacy of a vibrating mesh nebulizer and a jet nebulizer under different configurations

L Pitance, L Vecellio, T Leal, G Reychler… - Journal of aerosol …, 2010 - liebertpub.com
Background: Jet nebulizers coupled to spacers are frequently used to promote drug lung
deposition, but their clinical efficacy has not been established. Few in vivo studies have …

Comparison of breath-enhanced to breath-actuated nebulizers for rate, consistency, and efficiency

K Leung, E Louca, AL Coates - Chest, 2004 - Elsevier
Objectives: To evaluate differences between three new-generation nebulizers—Pari LC Star
(Pari Respiratory Equipment; Mississauga, ON, Canada), AeroEclipse (Trudell Medical …

The science of aerosol delivery in cystic fibrosis

DE Geller - Pediatric Pulmonology, 2008 - Wiley Online Library
Aerosolized drugs are universally used for treatment of cystic fibrosis airway disease.
Inhalation can increase topical efficacy and reduce systemic exposure and toxicity of many …