Novel 2-substituted-quinoxaline analogs with potential antiproliferative activity against breast cancer: insights into cell cycle arrest, topoisomerase II, and EGFR activity

MG Salem, SAA El-Ata, EH Elsayed, SN Mali… - RSC …, 2023 - pubs.rsc.org
Breast cancer is a global health concern, with increasing disease burden and disparities in
access to healthcare. Late diagnosis and limited treatment options in underserved areas …

[HTML][HTML] Formulation, optimization and evaluation of ocular gel containing nebivolol Hcl-loaded ultradeformable spanlastics nanovesicles: in vitro and in vivo studies

M Yasser, EE El Naggar, N Elfar, MH Teaima… - International Journal of …, 2024 - Elsevier
The study aims to improve the ocular delivery of Nebivolol HCL (NBV) belonging to the
Biopharmaceutics classification system (BCSII) by using spanlastic nanovesicles (SNVs) for …

Intranasal bilosomes in thermosensitive hydrogel: advancing desvenlafaxine succinate delivery for depression management

TM El-Nawawy, YA Adel, M Teaima… - Pharmaceutical …, 2024 - Taylor & Francis
Depression, the second biggest cause of disability worldwide, is widespread. Many
antidepressant medications, including Desvenlafaxine Succinate (DVS), function by …

[HTML][HTML] Enhanced Antibacterial Activity of Clindamycin Using Molecularly Imprinted Polymer Nanoparticles Loaded with Polyurethane Nanofibrous Scaffolds for the …

SF Elhabal, R Abdelmonem, RM El Nashar… - Pharmaceutics, 2024 - mdpi.com
Acne vulgaris, a prevalent skin condition, arises from an imbalance in skin flora, fostering
bacterial overgrowth. Addressing this issue, clindamycin molecularly imprinted polymeric …

Revolutionizing Psoriasis Topical Treatment: Enhanced Efficacy Through Ceramide/Phospholipid Composite Cerosomes Co-Delivery of Cyclosporine and Dithranol …

SF Elhabal, N Abdelaal, SAS Al-Zuhairy… - International Journal …, 2024 - Taylor & Francis
Purpose Improving the treatment of psoriasis is a serious challenge today. Psoriasis is an
immune-mediated skin condition affecting 125 million people worldwide. It is commonly …

Green Synthesis of Zinc Oxide Nanoparticles from Althaea officinalis Flower Extract Coated with Chitosan for Potential Healing Effects on Diabetic Wounds by …

SF Elhabal, N Abdelaal… - International Journal …, 2024 - Taylor & Francis
Background Diabetes Mellitus is a multisystem chronic pandemic, wound inflammation, and
healing are still major issues for diabetic patients who may suffer from ulcers, gangrene, and …

Unveiling the multifaceted antiproliferative efficacy of Cichorium endivia root extract by dual modulation of apoptotic and inflammatory genes, inducing cell cycle arrest …

AR Alzahrani, N Hosny, DI Mohamed, HHA Nahas… - RSC …, 2024 - pubs.rsc.org
Chicory (Cichorium endivia L. divaricatum) is a renowned medicinal plant traditionally used
for various ailments, yet the pharmacological potential of its roots, particularly in terms of …

Transdermal fluocinolone acetonide loaded decorated hyalurosomes cellulose acetate/polycaprolactone nanofibers mitigated Freund's adjuvant-induced rheumatoid …

SF ELhabal, MA El-Nabarawi, SO Hassanin… - Journal of …, 2024 - Springer
Purpose This study aimed to develop a transdermal delivery system for fluocinolone
acetonide (FLA), a corticosteroid used in treating inflammatory conditions like rheumatoid …