Cooperation of liver cells in health and disease: with 18 tables

Z Kmiec - 2001 - books.google.com
It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer
cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better …

Role of thyroglobulin endocytic pathways in the control of thyroid hormone release

M Marinò, RT McCluskey - American Journal of Physiology …, 2000 - journals.physiology.org
Thyroglobulin (Tg), the thyroid hormone precursor, is synthesized by thyrocytes and
secreted into the colloid. Hormone release requires uptake of Tg by thyrocytes and …

[HTML][HTML] Role of megalin (gp330) in transcytosis of thyroglobulin by thyroid cells: a novel function in the control of thyroid hormone release

M Marinò, G Zheng, L Chiovato, A Pinchera… - Journal of Biological …, 2000 - ASBMB
When thyroglobulin (Tg) is endocytosed by thyrocytes and transported to lysosomes, thyroid
hormones (T4 and T3) are released. However, some internalized Tg is transcytosed intact …

Extracellularly occurring histone H1 mediates the binding of thyroglobulin to the cell surface of mouse macrophages.

K Brix, W Summa, F Lottspeich… - The Journal of clinical …, 1998 - Am Soc Clin Investig
Thyroglobulin is the major secretory protein of thyroid epithelial cells. Part of thyroglobulin
reaches the circulation of vertebrates by transcytosis across the epithelial wall of thyroid …

The emerging roles of thyroglobulin

Y Luo, Y Ishido, N Hiroi, N Ishii… - Advances in …, 2014 - Wiley Online Library
Thyroglobulin (Tg), the most important and abundant protein in thyroid follicles, is well
known for its essential role in thyroid hormone synthesis. In addition to its conventional role …

Effect of thyroglobulin autoantibodies on the metabolic clearance of serum thyroglobulin

F Latrofa, D Ricci, S Bottai, F Brozzi, L Chiovato… - Thyroid, 2018 - liebertpub.com
Background: In order to establish whether thyroglobulin autoantibodies (TgAb) influence the
metabolic clearance of thyroglobulin (Tg) in humans, serum Tg and TgAb were correlated …

Effects of Calorie Restriction and Fasting on Macrophage: Potential Impact on Disease Outcomes?

L Wang, R Wang, X Yu, Y Shi, S Li… - Molecular Nutrition & …, 2023 - Wiley Online Library
Energy restriction, including calorie restriction and fasting, has garnered significant attention
for its potential therapeutic effects on a range of chronic diseases (such as diabetes, obesity …

Thyroglobulin storage, processing and degradation for thyroid hormone liberation

K Brix, M Qatato, J Szumska, V Venugopalan… - The Thyroid and Its …, 2019 - Springer
The tasks of the thyroid gland comprise (1) thyroid hormone (TH) generation via synthesis of
the prohormone thyroglobulin (Tg),(2) import and organification of iodine resulting in the …

Thyroglobulin increases cell proliferation and suppresses Pax-8 in mesangial cells

DF Sellitti, K Suzuki, SQ Doi, C LaGranha… - Biochemical and …, 2001 - Elsevier
Thyroglobulin (Tg), has recently been identified as a transcriptional regulator of thyroid-
restricted genes. The extrathyroidal expression of several of these genes (including the …

[HTML][HTML] Molecular evidence reveals thyrotropin intervention enhances the risk of developing radioiodine-refractory differentiated thyroid carcinoma

H Samimi, V Haghpanah - Cancer Cell International, 2022 - Springer
Radioiodine (RAI) is the mainstay of treatment for differentiated thyroid carcinoma (DTC)
following total thyroidectomy. Nevertheless, about 5% of patients with DTC are RAI …