Over the past five decades, those interested in markers of radiation effect have focused
primarily on tumor response. More recently, however, the view has broadened to include …

Chronic inflammation is one of the main features of cancer cachexia. Experimental and
clinical studies showed that cyclooxygenase-2 inhibitors, such as celecoxib, may be …

Purpose Glioblastoma multiforme (GBM) represents the prototype of an angiogenic tumor.
Recently, the continuous low-dose scheduling of chemotherapeutic drugs in combination …

Fairly advanced clinical data on efficacy of cyclooxygenase-2 inhibitors and antioxidants in
advanced cancer patients are promising, but the best way to administer and combine them …

Rofecoxib is an inhibitor of the enzyme cyclo‐oxygenase 2 (COX‐2) used as an analgesic
and anti‐inflammatory agent especially in rheumatoid arthritis and osteoarthritis. The …

Abstract Purpose: Cyclooxygenase-2 (COX-2) is generally elevated in tumors compared
with normal tissue and apparently has an important role in tumor development. A number of …

Purpose: To determine whether lumiracoxib, a highly selective cyclooxygenase-2 (COX-2)
inhibitor that exhibits anti-inflammatory and antiangiogenic properties, can inhibit …

To evaluate the direct effect of human cyclooxygenase-2 (hCox-2) on human breast tumor
cell proliferation, invasion, and angiogenesis, hCox-2 cDNA was transfected into slow …

Carcinogenesis is a multistep process of long-term accumulation of genetic and epigenetic
aberrations at the molecular level. Understanding the mechanisms underlying …

Hypertension and cancer are two leading diseases in the world. Often they coexist in
patients. They share some common predisposing factors eg, ageing, obesity, alcohol …