Adverse outcome pathways (AOPs) organize knowledge on the progression of toxicity
through levels of biological organization. By determining the linkages between toxicity …

Current evidence supports the notion that environmental exposures are associated with
DNA-methylation and expression changes that can impact human health. Our objective was …

Nanoplastics with small particle sizes and high surface area/volume ratios easily absorb
environmental pollutants and affect their bioavailability. In this study, polystyrene nanoplastic …

Micropollutants, as a serious water pollution issue, raise considerable toxicological
concerns, particularly when present as components of complex mixtures. Due to the …

Epigenetic changes constitute one of the processes that is involved in the mechanisms of
carcinogenicity. They include dysregulation of DNA methylation processes, disruption of …

Epigenetics can play a role in interactions between chemicals and exposed species,
between species and abiotic ecosystem components or between species of the same or …

Abstract Benzo [a] pyrene (B [a] P) is a well-known genotoxic polycylic aromatic compound
whose toxicity is dependent on signaling via the aryl hydrocarbon receptor (AHR). It is …

In the aquatic environment, adverse outcomes from dietary polycyclic aromatic hydrocarbon
(PAH) exposure are poorly understood, and multigenerational developmental effects …

1. Introduction 2. Molecular Regulation of the Hypothalamic–Pituitary–Interrenal (HPI) Axis
2.1. Hypothalamus 2.2. Pituitary 2.3. Head Kidney (Interrenal Tissue) 3. Genomic Cortisol …

The heritable component of breast cancer accounts for only a small proportion of total
incidences. Environmental and lifestyle factors are therefore considered to among the major …