[HTML][HTML] Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in …
Adverse outcome pathways (AOPs) organize knowledge on the progression of toxicity
through levels of biological organization. By determining the linkages between toxicity …
through levels of biological organization. By determining the linkages between toxicity …
[HTML][HTML] Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence
A Ruiz-Hernandez, CC Kuo, P Rentero-Garrido… - Clinical …, 2015 - Springer
Current evidence supports the notion that environmental exposures are associated with
DNA-methylation and expression changes that can impact human health. Our objective was …
DNA-methylation and expression changes that can impact human health. Our objective was …
Effects of nanoplastics and butyl methoxydibenzoylmethane on early zebrafish embryos identified by single-cell RNA sequencing
Y Liu, Y Wang, X Ling, Z Yan, D Wu… - … Science & Technology, 2021 - ACS Publications
Nanoplastics with small particle sizes and high surface area/volume ratios easily absorb
environmental pollutants and affect their bioavailability. In this study, polystyrene nanoplastic …
environmental pollutants and affect their bioavailability. In this study, polystyrene nanoplastic …
Toxicity of 10 organic micropollutants and their mixture: Implications for aquatic risk assessment
Micropollutants, as a serious water pollution issue, raise considerable toxicological
concerns, particularly when present as components of complex mixtures. Due to the …
concerns, particularly when present as components of complex mixtures. Due to the …
[HTML][HTML] Influence of benzo (a) pyrene on different epigenetic processes
B Bukowska, P Sicińska - International Journal of Molecular Sciences, 2021 - mdpi.com
Epigenetic changes constitute one of the processes that is involved in the mechanisms of
carcinogenicity. They include dysregulation of DNA methylation processes, disruption of …
carcinogenicity. They include dysregulation of DNA methylation processes, disruption of …
Epigenetics in an ecotoxicological context
MB Vandegehuchte, CR Janssen - Mutation Research/Genetic Toxicology …, 2014 - Elsevier
Epigenetics can play a role in interactions between chemicals and exposed species,
between species and abiotic ecosystem components or between species of the same or …
between species and abiotic ecosystem components or between species of the same or …
[HTML][HTML] Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo [a] pyrene in zebrafish
Abstract Benzo [a] pyrene (B [a] P) is a well-known genotoxic polycylic aromatic compound
whose toxicity is dependent on signaling via the aryl hydrocarbon receptor (AHR). It is …
whose toxicity is dependent on signaling via the aryl hydrocarbon receptor (AHR). It is …
Multigenerational effects of benzo [a] pyrene exposure on survival and developmental deformities in zebrafish larvae
J Corrales, C Thornton, M White, KL Willett - Aquatic toxicology, 2014 - Elsevier
In the aquatic environment, adverse outcomes from dietary polycyclic aromatic hydrocarbon
(PAH) exposure are poorly understood, and multigenerational developmental effects …
(PAH) exposure are poorly understood, and multigenerational developmental effects …
The molecular stress response
1. Introduction 2. Molecular Regulation of the Hypothalamic–Pituitary–Interrenal (HPI) Axis
2.1. Hypothalamus 2.2. Pituitary 2.3. Head Kidney (Interrenal Tissue) 3. Genomic Cortisol …
2.1. Hypothalamus 2.2. Pituitary 2.3. Head Kidney (Interrenal Tissue) 3. Genomic Cortisol …
[HTML][HTML] Endocrine disruption of the epigenome: a breast cancer link
The heritable component of breast cancer accounts for only a small proportion of total
incidences. Environmental and lifestyle factors are therefore considered to among the major …
incidences. Environmental and lifestyle factors are therefore considered to among the major …