miRNAs role in cervical cancer pathogenesis and targeted therapy: Signaling pathways interplay

AS Doghish, MA Ali, SS Elyan, MA Elrebehy… - … -Research and Practice, 2023 - Elsevier
Cervical cancer (CC) is the primary cause of cancer deaths in underdeveloped countries.
The persistence of infection with high-risk human papillomavirus (HPV) is a significant …

microRNAs: new prognostic, diagnostic, and therapeutic biomarkers in cervical cancer

JS Nahand, S Taghizadeh‐boroujeni… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer
could be observed in women who infected with papillomavirus, regular oral contraceptives …

LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR

J Kim, K Abdelmohsen, X Yang, S De… - Nucleic acids …, 2016 - academic.oup.com
The function of the vast majority of mammalian long noncoding (lnc) RNAs remains
unknown. Here, analysis of a highly abundant mammalian lncRNA, OIP5-AS1, known as …

[HTML][HTML] MiR-125a suppresses tumor growth, invasion and metastasis in cervical cancer by targeting STAT3

Z Fan, H Cui, X Xu, Z Lin, X Zhang, L Kang, B Han… - Oncotarget, 2015 - ncbi.nlm.nih.gov
MiR-125a has been characterized as a tumor suppressor in several cancers. However, the
role of miR-125a in cervical cancer is unknown. In this study, we found the expression of …

Non-coding RNAs related to angiogenesis in gynecological cancer

N Rahimian, ZS Razavi, F Aslanbeigi… - Gynecologic …, 2021 - Elsevier
Gynecological cancer affects the female reproductive system, including ovarian, uterine,
endometrial, cervical, vulvar, and vaginal tumors. Non-coding RNAs (ncRNAs), and in …

[HTML][HTML] miR-342-3p suppresses proliferation, migration and invasion by targeting FOXM1 in human cervical cancer

X Li, H Chu, T Lv, L Wang, S Kong, S Dai - FEBS letters, 2014 - Elsevier
FOXM1 is a well-established oncogenic factor that has been reported to be involved in
multiple biological processes including cell proliferation, growth, angiogenesis, migration …

MiR-361-5p inhibits glycolytic metabolism, proliferation and invasion of breast cancer by targeting FGFR1 and MMP-1

F Ma, L Zhang, L Ma, Y Zhang, J Zhang… - Journal of Experimental & …, 2017 - Springer
Background MicroRNAs function as key regulators in various human cancers, including
breast cancer (BC). MiR-361-5p has been proved to be a tumor suppressor in colorectal …

Targeting aldehyde dehydrogenases to eliminate cancer stem cells in gynecologic malignancies

V Muralikrishnan, TD Hurley, KP Nephew - Cancers, 2020 - mdpi.com
Gynecologic cancers cause over 600,000 deaths annually in women worldwide. The
development of chemoresistance after initial rounds of chemotherapy contributes to tumor …

MiR-486-3p targeting ECM1 represses cell proliferation and metastasis in cervical cancer

H Ye, X Yu, J Xia, X Tang, L Tang, F Chen - Biomedicine & …, 2016 - Elsevier
MicroRNAs (miRNAs) regulate gene expression and are involved in cervical cancer. But the
molecular mechanism is still unclear. Here, miRNA profile of cervical cancer was performed …

Cervical cancer development, chemoresistance, and therapy: a snapshot of involvement of microRNA

T Mitra, S Elangovan - Molecular and Cellular Biochemistry, 2021 - Springer
Cervical cancer (CC) is one of the leading causes of death in women due to cancer and a
major concern in the developing world. Persistent human papilloma virus (HPV) infection is …